Table 2 Vascular assessments before and after rosuvastatin treatment in SSc patients
Parameter | Pre-treatment mean (S.D.) | Post-treatment mean (S.D.) | P valuea |
|---|---|---|---|
FMD (%) | 2.3 (3.3) | 5.7 (3.9) | 0.0002 |
Right ccIMT (mm) | 0.675 (0.144) | 0.681 (0.142) | ns (0.38) |
Left ccIMT (mm) | 0.717 (0.172) | 0.701 (0.165) | ns (0.3) |
Carotid-femoral PWV (m/s) | 8.7 (2.6) | 8.1 (1.9) | ns (0.1) |
Aorto-femoral PWV (m/s) | 8.8 (2.2) | 8.3 (2.1) | ns (0.15) |
Right Ankle-Brachial Index | 1.1 (0.16) | 1.1 (0.27) | ns (0.4) |
Left Ankle-Brachial Index | 1.1 (0.14) | 1.1 (0.19) | ns (0.4) |
Laser Doppler acceleration slope (U/s) | 14.6 (14.8) | 10.0 (10.3) | ns (0.08) |
Laser Doppler deceleration slope (U/s) | -1.13 (0.92) | -0.64 (1.09) | 0.021 |