Table 1 Studies assessing the relationship between functional and morphological measures of endothelial function.
Authors | Participants | Vascular assessment | Associations |
|---|---|---|---|
Healthy | Â | Â | Â |
Juonala et al. 2004 [52] | 2109 healthy (age: 32 ± 5 years) | FMD, cIMT | FMD inversely associated with cIMT |
Yeboah et al. 2008 [29] | 2338 healthy (age 78 ± 4) | FMD, cIMT | No significant associations |
Koivistoinen et al. 2012 [30] | 1754 healthy (young) (age: 30 - 45) & 336 healthy (older) (age: 46 - 76) | FMD, PWV, cIMT | No significant associations |
Lunder et al. 2012 [50] | 100 healthy males (age: 42 ± 6) | FMD, GTN, PWV, cIMT | FMD inversely associated with PWV |
Irace et al. 2006 [31] | 77 healthy | FMD, GTN, cIMT | No significant associations |
Yan et al. 2005 [32] | 1,578 healthy males (age: 49 ± 10) | FMD, GTN, cIMT | No significant associations |
Coronary artery disease | Â | Â | Â |
Rohani et al. 2005 [39] | 58 CAD (age: 67 ± 9) | FMD, cIMT, carotid plaque | No significant associations |
Simova et al. 2008 [33] | 198 CAD (age: 60 ± 10 | FMD, cIMT | FMD inversely associated with cIMT |
Furumoto et al. 2002 [34] | 45 CAD (age: 61 ± 11) | FMD, GTN, cIMT | FMD inversely associated with cIMT |
Hashimoto et al. 1999 [53] | 34 CAD males (age: 61 ± 2) & 33 age-matched healthy controls | FMD, GTN, cIMT | FMD inversely associated with cIMT when both populations combined, and when analysis was performed in healthy controls only & GTN inversely associated with cIMT when both populations combined |
Enderle et al. 1998 [54] | 101 CAD (age: 60 ± 8.6) & 21 non-CAD (age: 57 ± 8.2) | FMD, GTN, cIMT | FMD inversely associated with cIMT |
Diabetes | Â | Â | Â |
Ravikumar et al. 2002 [55] | 50 diabetics (age: 54 ± 10) & 50 healthy age- & sex-matched controls | FMD, AIx, cIMT | FMD inversely associated with AIx and cIMT when both populations combined, and when analysis was performed in healthy controls only & FMD inversely associated with AIx in diabetics |
Rheumatoid arthritis | Â | Â | Â |
Arosio et al. 2007 [23] | 65 RA females (age: 41 - 52) | FMD, PWV | FMD inversely associated with PWV in RA |
Kerekes et al. 2008 [25] | 52 RA (age: 51 ± 12) | FMD, GTN, cIMT | FMD inversely associated with cIMT |
Soltesz et al. 2009 [24] | 101 patients with autoimmune disease (age: 52 ± 13) | FMD, AIx, PWV, cIMT | FMD inversely associated with AIx, PWV and cIMT |
Van Doornum et al. 2003 [60] | 25 RA (age: 46 ± 8) | FMD, GTN, PWA | FMD not associated with PWA |