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Table 2 Values of lactate release in cultures of normal chondrocytes treated with different NO donors compounds for 24 hours

From: Nitric oxide compounds have different effects profiles on human articular chondrocyte metabolism

  Lactate
(μM/5 × 104 cells)
Control normal chondrocytes 2.30 ± 0.58 (7)
0.5 mM SNP 1.83 ± 0.65 (7)
1 mM SNP 1.33 ± 0.38 (7) †
2 mM SNP 1.01 ± 0.30 (7) †
0.5 mM NOC-12 2.91 ± 0.58 (7)
1 mM NOC-12 2.90 ± 0.66 (7)
2 mM NOC-12 2.86 ± 0.77 (7)
  1. Values are the mean ± SD (number). NO, nitric oxide; SNP, sodium nitroprusside; NOC-12, N-ethyl-2(1-ethyl-2 hydroxy-2-nitrosohydrazine.