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Table 2 Values of lactate release in cultures of normal chondrocytes treated with different NO donors compounds for 24 hours

From: Nitric oxide compounds have different effects profiles on human articular chondrocyte metabolism

 

Lactate

(μM/5 × 104 cells)

Control normal chondrocytes

2.30 ± 0.58 (7)

0.5 mM SNP

1.83 ± 0.65 (7)

1 mM SNP

1.33 ± 0.38 (7) †

2 mM SNP

1.01 ± 0.30 (7) †

0.5 mM NOC-12

2.91 ± 0.58 (7)

1 mM NOC-12

2.90 ± 0.66 (7)

2 mM NOC-12

2.86 ± 0.77 (7)

  1. Values are the mean ± SD (number). NO, nitric oxide; SNP, sodium nitroprusside; NOC-12, N-ethyl-2(1-ethyl-2 hydroxy-2-nitrosohydrazine.