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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Dynamic pressurization induces transition of notochordal cells to a mature phenotype while retaining production of important patterning ligands from development

Figure 4

Gene expression for notochordal cell phenotypic markers. Quantitative reverse transcription real-time polymerase chain reaction was performed to assess fold-changes in gene expression in the1 Dose and Daily pressurization groups normalized to unloaded controls and housekeeping gene 18s. No significant changes were observed in Brachyury (T), K18, or matrix proteins (Aggrecan and Col1a1 and Col2a1), but there was a significant increase in Noggin expression with the Daily and 1 Dose load groups compared with the unloaded Control group (*P < 0.05).

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