Figure 1

FOI images of a female RA patient. Fluorescence optical imaging composite images of the hands of a female patient with rheumatoid arthritis: (A) phase 1 (1 to 120 seconds); (B) phase 2 (121 to 240 seconds), and (C) phase 3 (241 to 360 seconds). Depicted are the placement of the regions of interest for the carpal, metacarpalphalangeal (MCP), and proximal interphalangeal (PIP) joint of the index (II) and middle (III) fingers and the control region at the eponychium of the index finger (white arrow).