Arthritis Research & Therapy

Table 2 Mean fluorescence readout for joints with compared to those without evidence of synovitis determined by clinical examination or established imaging techniques ^#

From: Quantitative assessment of synovitis in patients with rheumatoid arthritis using fluorescence optical imaging

		FOI phase 1 (1 – 120 seconds)		FOI phase 2 (121 – 240 seconds)		FOI phase 3 (241 – 360 seconds)
Synovitis	n	*mean ± SD*	P	*mean ± SD*	P	*mean ± SD*	P
TJ yes	44	19.1 ± 11.0	ns	19.6 ± 9.0	ns	12.6 ± 5.7	ns
TJ no	46	19.2 ± 7.8	ns	19.6 ± 9.4	ns	13.0 ± 7.8	ns
SJ yes	26	22.7 ± 12.6	ns	22.3 ± 9.8	ns	14.1 ± 6.2	ns
SJ no	64	17.7 ± 7.5	ns	18.5 ± 8.7	ns	12.3 ± 7.0	ns
GSUS yes	39	21.0 ± 11.4	ns	23.5 ± 10.4	**	15.8 ± 7.9	**
GSUS no	51	17.7 ± 7.5	ns	16.6 ± 6.8	**	10.5 ± 4.8	**
CDUS yes	23	24.1 ± 12.3	*	23.8 ± 9.3	*	15.0 ± 5.9	ns
CDUS no	67	17.5 ± 7.7	*	18.2 ± 8.7	*	12.0 ± 7.0	ns
MRI yes	39^§	20.9 ± 10.1	ns	22.3 ± 9.5	*	14.8 ± 7.3	*
MRI no	40^§	17.8 ± 9.6	ns	17.2 ± 9.2	*	10.9 ± 6.5	*
All	90	19.1 ± 9.4		19.6 ± 9.2		12.8 ± 6.8

^# Fluorescence readout results are displayed for better readability divided by 10³; ^§ 11 joints could not be evaluated with MRI; ^*P<0.05; ^**P<0.01.
CDUS color Doppler ultrasonography, FOI fluorescence optical imaging, GSUS grey-scale ultrasonography, MRI magnetic resonance imaging; ns, comparison was not significant (P≥0.05 with student’s t-test), SD standard deviation, SJ swollen joint by clinical examination, TJ tender joint by clinical examination.

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