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Table 3 Independent relations of total adiponectin concentrations* with cardiometabolic risk and surrogate markers of enhanced early atherogenesis in African black and white patients with rheumatoid arthritis

From: Independent associations of total and high molecular weight adiponectin with cardiometabolic risk and surrogate markers of enhanced early atherogenesis in black and white patients with rheumatoid arthritis: a cross-sectional study

   

Patients

 

Interaction

All (n = 210)

Black (n = 119)

White (n = 91)

Characteristic

Partial R

P

Partial R

P

Partial R

P

Partial R

P

Metabolic risk factor

        

 Systolic blood pressure

0.039

0.6

0.232

0.001

0.304

0.001

0.157

0.1

 Diastolic blood pressure

-0.032

0.7

0.203

0.004

0.248

0.01

0.200

0.07

 Mean blood pressure

0.026

0.7

0.241

0.008

0.298

0.002

0.181

0.1

 Total cholesterol

-0.139

0.06

-0.164

0.02

-0.138

0.1

-0.213

0.06

 HDL cholesterol*

0.201

0.005

0.126

0.08

0.360

0.002

-0.170

0.1

 Total-HDL cholesterol ratio

-0.270

0.0002

-0.231

0.001

-0.390

<0.0001

-0.027

0.9

 LDL cholesterol

-0.131

0.07

-0.158

0.03

-0.178

0.08

-0.142

0.2

 Non-HDL cholesterol

-0.244

0.0007

-0.209

0.004

-0.292

0.003

-0.132

0.2

 Triglycerides*

-0.204

0.005

-0.231

0.003

-0.299

0.002

-0.060

0.5

 Triglycerides-HDL cholesterol ratio*

-0.254

0.0004

-0.221

0.002

-0.379

<0.0001

0.045

0.7

 Glucose*

-0.104

0.1

-0.126

0.08

-0.109

0.3

-0.304

0.006

 Number of metabolic risk factors

-0.244

0.0007

-0.120

0.1

-0.238

0.01

0.047

0.6

Early atherogenesis

        

 Selectin

-0.068

0.3

-0.040

0.6

-0.062

0.5

-0.029

0.7

 VCAM-1*

-0.165

0.02

0.122

0.09

-0.020

0.8

0.262

0.01

 ICAM-1*

-0.109

0.1

0.012

0.9

-0.083

0.4

0.147

0.1

 MCP-1*

-0.122

0.09

0.100

0.2

-0.001

1.0

0.297

0.006

 Endothelial activation score

-0.203

0.005

0.080

0.3

-0.071

0.4

0.262

0.01

  1. Relationships were determined in demographic characteristic, log glomerular filtration, cardiovascular drug use and waist circumference adjusted models. Significant associations are shown in bold. *Log transformed. HDL, High density lipoprotein; ICAM, Intercellular adhesion molecule; LDL, Low density lipoprotein; MCP, Monocyte chemoattractant protein; VCAM, Vascular cell adhesion molecule.