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Table 3 Blood pressure phenotypic phenomena and vascular damage in patients with rheumatoid arthritis a

From: Arterial hypertension assessed “out-of-office” in a contemporary cohort of rheumatoid arthritis patients free of cardiovascular disease is characterized by high prevalence, low awareness, poor control and increased vascular damage-associated “white coat” phenomenon

Characteristics SN (N= 97) WCH (N= 37) SH (N= 40) P
BP     
 Office SBP (mmHg) 115.1 ± 9.2 142.9 ± 11.1 151.8 ± 16.6  
 Office DBP (mmHg) 70.9 ± 5.8 82.2 ± 7.0 86.2 ± 9.5  
 Out-of-office SBP (mmHg) 123.7 ± 9.5 121.6 ± 7.3 141.2 ± 8.3  
 Out-of-office DBP (mmHg) 77.6 ± 3.4 72.4 ± 68 83.1 ± 10.0  
Vascular damage     
 L CCA CSA (mm2) 13.1 ± 3.0 14.5 ± 3.7 15.1 ± 3.2 0.002/0.251b
 R CCA CSA (mm2) 12.5 ± 2.8 14.0 ± 3.8 15.2 ± 2.7 <0.001/0.027b
 Presence of plaque (%) 49 59 72.5 0.044/0.354b
 PWV (m/s) 7.8 ± 1.7 8.9 ± 2.7 9.8 ± 2.7 <0.001/<0.001c
 L ABI (%) 1.23 ± 0.1 1.19 ± 0.9 1.21 ± 1.0 0.233
 R ABI (%) 1.22 ± 0.1 1.14 ± 0.1 1.18 ± 0.1 0.002/<0.001c
CV risk factors     
 Age, years 55.4 ± 12.7 59.7 ± 11.1 60.9 ± 10.8 0.026
 Females (%) 86 84 70 0.067
 DM (%) 6 5 5 0.923
 Current smokers (%)     0.036
   Current 38 16 25  
   Ex-smokers 14 19 30  
 Dyslipidemia (%) 18 24 30 0.328
 BMI (kg/m2) 25.5 ± 4.8 28.1 ± 4.3 28.1 ± 5.7 0.003
  1. aABI, Ankle-Brachial Index; BMI, body mass index; BP, blood pressure; CCA, common carotid artery; CV, cardiovascular; CSA, cross-sectional surface area; DBP, diastolic blood pressure, DM, diabetes mellitus; L, left; R, right; SBP, systolic blood pressure; SH, sustained hypertension; SN, sustained normotension; WCH, white coat hypertension. bAdjusted for age, gender, BMI and smoking. cAdjusted for age, gender, BMI and smoking and for mean office BP. Data were analyzed by regression analysis, analysis of variance or analysis of covariance as appropriate. Data in the SN group are presented only for those patients who had high normal office BP and as a consequence were advised to measure out-of-office BP.