Table 1 Allelic frequencies of the HLA-A and HLA-B allele groups in Behçet’s disease patients and healthy controls a
From: HLA and non-HLA genes in Behçet’s disease: a multicentric study in the Spanish population
Region | BD patients | Controls | P | OR (95% CI) |
|---|---|---|---|---|
HLA-A | 2n = 542 (%) | 2n = 626 (%) | ||
01 | 51 (0.09) | 63 (0.10) | ||
02 | 186 (0.34) | 164 (0.26) | 0.003 | 1.47 (1.14 to 1.91) |
03 | 34 (0.06) | 70 (0.11) | 0.003 | 0.53 (0.34 to 0.83) |
11 | 31 (0.06) | 47 (0.08) | ||
23 | 20 (0.04) | 25 (0.04) | ||
24 | 59 (0.11) | 42 (0.07) | 0.01 | 1.70 (1.10 to 2.62) |
25 | 3 (0.005) | 8 (0.01) | ||
26 | 19 (0.03) | 27 (0.04) | ||
29 | 40 (0.07) | 50 (0.08) | ||
30 | 23 (0.04) | 33 (0.05) | ||
31 | 19 (0.03) | 13 (0.02) | ||
32 | 18 (0.03) | 22 (0.03) | ||
33 | 11 (0.02) | 20 (0.03) | ||
34 | 2 (0.004) | 0 (0.0) | ||
36 | 1 (0.002) | 0 (0.0) | ||
66 | 7 (0.01) | 5 (0.008) | ||
68 | 16 (0.03) | 32 (0.05) | ||
69 | 1 (0.002) | 4 (0.006) | ||
80 | 1 (0.002) | 1 (0.002) | ||
HLA-B | 2n = 548 (%) | 2n = 626 (%) | ||
07 | 34 (0.06) | 40 (0.06) | ||
08 | 25 (0.05) | 25 (0.04) | ||
13 | 5 (0.009) | 5 (0.008) | ||
14 | 35 (0.06) | 57 (0.09) | ||
15 | 35 (0.06) | 24 (0.04) | ||
18 | 29 (0.05) | 55 (0.09) | 0.02 | 0.58 (0.35 to 0.95) |
27 | 16 (0.03) | 19 (0.03) | ||
35 | 36 (0.07) | 78 (0.12) | 0.0007 | 0.49 (0.32 to 0.76) |
37 | 3 (0.005) | 3 (0.004) | ||
38 | 12 (0.02) | 28 (0.04) | 0.03 | 0.48 (0.23 to 0.99) |
39 | 5 (0.009) | 10 (0.02) | ||
40 | 14 (0.02) | 22 (0.03) | ||
41 | 5 (0.009) | 7 (0.01) | ||
42 | 1 (0.002) | 0 (0.0) | ||
44 | 70 (0.13) | 88 (0.14) | ||
45 | 8 (0.01) | 16 (0.03) | ||
46 | 1 (0.002) | 0 (0.0) | ||
47 | 1 (0.002) | 1 (0.002) | ||
48 | 0 (0.0) | 2 (0.003) | ||
49 | 17 (0.03) | 35 (0.06) | ||
50 | 13 (0.02) | 20 (0.03) | ||
51 | 125 (0.23) | 42 (0.07) | <10–7 | 4.11 (2.79 to 6.06) |
52 | 5 (0.009) | 8 (0.01) | ||
53 | 8 (0.01) | 14 (0.02) | ||
54 | 0 (0.0) | 1 (0.002) | ||
55 | 6 (0.01) | 3 (0.005) | ||
56 | 4 (0.007) | 1 (0.002) | ||
57 | 34 (0.06) | 11 (0.02) | 0.00008 | 3.70 (1.78 to 7.83) |
58 | 1 (0.002) | 11 (0.02) | 0.007 | 0.10 ( 0.0 to 0.71) |