Skip to main content

Table 4 One-locus analysis of the non–human leukocyte antigen genes included in this study a

From: HLA and non-HLA genes in Behçet’s disease: a multicentric study in the Spanish population

SNPs Location BD patients Controls P OR (95% CI)
LOC100129342      
 rs11206377 Chr1:39821691     
   A   280 (0.48) 279 (0.45)   
   G   306 (0.52) 347 (0.55) >0.05  
IL23R      
 rs17375018 Chr1: 67427735     
   A   149 (0.26) 197 (0.32)   
   G   431 (0.74) 415 (0.68) 0.01 1.37 (1.06-1.78)
 rs7517847 Chr1:67454257     
   G   189 (0.33) 272 (0.43)   
   T   391 (0.67) 354 (0.57) 0.0001 1.59 (1.25-2.02)
 rs1343151 Chr1:67491717     
   A   192 (0.33) 250 (0.40)   
   G   390 (0.67) 374 (0.60) 0.01 1.36 (1.07-1.73)
IL10      
 rs3024498 Chr1: 205008152     
   C   89 (0.15) 115 (0.18)   
   T   495 (0.85) 507 (0.82) >0.05  
 rs2222202 Chr1:205012004     
   A   200 (0.34) 254 (0.41)   
   G   388 (0.66) 366 (0.59) 0.01 1.35 (1.06-1.71)
 rs1800872 Chr1:205013030     
   A   172 (0.30) 157 (0.25)   
   C   408 (0.70) 463 (0.75) >0.05  
CPVL      
 rs317711 Chr7:29068833     
   C   143 (0.25) 164 (0.27)   
   G   429 (0.75) 454 (0.73) >0.05  
TDRD7      
 rs2061634 Chr9:99145603     
   C   453 (0.79) 468 (0.75)   
   G   123 (0.21) 154 (0.25) >0.05  
UBASH3B      
 rs4936742 Chr11:12214629     
   C   302 (0.54) 327 (0.53)   
   T   258 (0.46) 291 (0.47) >0.05  
UBAC2      
 rs7999348 Chr13:98730923     
   A   407 (0.71) 430 (0.70)   
   G   169 (0.29) 182 (0.30) >0.05  
  1. aBD, Behçet’s disease; CI, confidence interval; OR, odds ratio; Pc, conditional probability; SNP, single-nucleotide polymorphism. An allelic model was used. Allelic frequencies are the number of each specific allele divided by the total number of alleles (number of individuals × 2) are shown within the parentheses.