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Table 4 One-locus analysis of the non–human leukocyte antigen genes included in this study a

From: HLA and non-HLA genes in Behçet’s disease: a multicentric study in the Spanish population

SNPs

Location

BD patients

Controls

P

OR (95% CI)

LOC100129342

     

 rs11206377

Chr1:39821691

    

   A

 

280 (0.48)

279 (0.45)

  

   G

 

306 (0.52)

347 (0.55)

>0.05

 

IL23R

     

 rs17375018

Chr1: 67427735

    

   A

 

149 (0.26)

197 (0.32)

  

   G

 

431 (0.74)

415 (0.68)

0.01

1.37 (1.06-1.78)

 rs7517847

Chr1:67454257

    

   G

 

189 (0.33)

272 (0.43)

  

   T

 

391 (0.67)

354 (0.57)

0.0001

1.59 (1.25-2.02)

 rs1343151

Chr1:67491717

    

   A

 

192 (0.33)

250 (0.40)

  

   G

 

390 (0.67)

374 (0.60)

0.01

1.36 (1.07-1.73)

IL10

     

 rs3024498

Chr1: 205008152

    

   C

 

89 (0.15)

115 (0.18)

  

   T

 

495 (0.85)

507 (0.82)

>0.05

 

 rs2222202

Chr1:205012004

    

   A

 

200 (0.34)

254 (0.41)

  

   G

 

388 (0.66)

366 (0.59)

0.01

1.35 (1.06-1.71)

 rs1800872

Chr1:205013030

    

   A

 

172 (0.30)

157 (0.25)

  

   C

 

408 (0.70)

463 (0.75)

>0.05

 

CPVL

     

 rs317711

Chr7:29068833

    

   C

 

143 (0.25)

164 (0.27)

  

   G

 

429 (0.75)

454 (0.73)

>0.05

 

TDRD7

     

 rs2061634

Chr9:99145603

    

   C

 

453 (0.79)

468 (0.75)

  

   G

 

123 (0.21)

154 (0.25)

>0.05

 

UBASH3B

     

 rs4936742

Chr11:12214629

    

   C

 

302 (0.54)

327 (0.53)

  

   T

 

258 (0.46)

291 (0.47)

>0.05

 

UBAC2

     

 rs7999348

Chr13:98730923

    

   A

 

407 (0.71)

430 (0.70)

  

   G

 

169 (0.29)

182 (0.30)

>0.05

 
  1. aBD, Behçet’s disease; CI, confidence interval; OR, odds ratio; Pc, conditional probability; SNP, single-nucleotide polymorphism. An allelic model was used. Allelic frequencies are the number of each specific allele divided by the total number of alleles (number of individuals × 2) are shown within the parentheses.