Repeated autologous intraarticular blood injections as an animal model for joint pain in haemophilic arthropathy

Table 1 Quantitative gait parameters (injected side)

Distance left to right paw (stride length) [cm]
Test day	BL	1	8	15	22	29	36	43	50
Saline	5.4 ± 0.1	5.2 ± 0.3	4.9 ± 0.4	5.2 ± 0.2	4.9 ± 0.4	4.9 ± 0.3	5.2 ± 0.3	4.9 ± 0.3	5.5 ± 0.2
WB	5.8 ± 0.2	5.8 ± 0.4	5.3 ± 0.3	5.0 ± 0.3	4.9 ± 0.2	5.0 ± 0.4	4.5 ± 0.3	5.1 ± 0.5	4.9 ± 0.3
Plasma	5.6 ± 0.2	5.1 ± 0.3	5.3 ± 0.3	5.2 ± 0.3	5.1 ± 0.3	4.3 ± 0.3	4.5 ± 0.2	4.5 ± 0.3	4.4 ± 0.4
Cells	5.9 ± 0.2	5.4 ± 0.3	5.4 ± 0.3	5.4 ± 0.1	4.9 ± 0.3	4.8 ± 0.2	4.5 ± 0.4	5.0 ± 0.3	4.1 ± 0.3
Angle between paws (outward rotation) (°)
Test day	BL	1	8	15	22	29	36	43	50
Saline	30 ± 2	31 ± 2	31 ± 4	31 ± 3	28 ± 2	29 ± 2	31 ± 2	31 ± 2	30 ± 3
WB	32 ± 2	33 ± 3	32 ± 2	34 ± 2	32 ± 2	32 ± 2	36 ± 2	34 ± 1	32 ± 1
Plasma	32 ± 2	31 ± 2	32 ± 2	31 ± 1	32 ± 2	35 ± 2	34 ± 1	35 ± 3	33 ± 2
Cells	34 ± 2	37 ± 2	33 ± 2	35 ± 2	35 ± 2	32 ± 2	33 ± 2	36 ± 2	36 ± 2

Data are presented as mean ± SEM. There were no significant differences between groups. BL, baseline; SEM, standard error of the mean; WB, whole blood.

ISSN: 1478-6362