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Table 5 Biochemical parameters associated with antisynthetase syndrome deterioration a

From: Functional outcome and prognostic factors in anti-Jo1 patients with antisynthetase syndrome

Biochemical parameters

ASS remission/improvement

ASS deterioration

P

(n = 68)

(n = 18)

Overall

   

 ESR (mm/h)

20 (range: 2 to 108)

32 (range: 8 to 86)

0.09

 C-reactive protein (mg/L)

6 (range: 1 to 104)

13 (range: 3 to 212)

0.172

 Hemoglobin (g/dl)

13.1 (range: 9.8 to 16)

12.9 (range: 10.2 to 15)

1

 Total leukocyte count (giga/L)

6.9 (range: 2.5 to 20.7)

8.3 (range: 3.8 to 25.7)

0.443

 Alanine aminotransferase (IU/L)

57 (range: 11 to 368)

45 (range: 15 to 188)

0.763

 Aspartate aminotransferase (IU/L)

58 (range: 23 to 787)

70 (range: 12 to 376)

0.537

 Creatine kinase (IU/L)

492 (range: 24 to 20,000)

352 (range: 39 to 10,601)

0.861

 Anti-Jo1 antibody titer (U/ml)

   

  At initial diagnosis of ASS

69

98

0.033

  At last follow-up of ASS

47

135

0.018

  1. aASS: antisynthetase syndrome; ESR: erythrocyte sedimentation rate. Data are medians (ranges) unless otherwise specified. P values were calculated using Fisher’s exact test.