Table 1 Descriptive baseline characteristics of knees with medial tibia bone marrow lesion (BML) regression, progression, or no change
Variable | BML regression (n = 76) | No BML or no BML change (n = 156) | BML progression (n = 76) |
|---|---|---|---|
| Â | Median (Min, Max) or n(%) | Median (Min, Max) or n(%) | Median (Min, Max) or n(%) |
Age (years) | 65 (50, 81) | 61 (48, 82) | 68 (48, 82) |
Body mass index (kg/m2) | 29.3 (21.1, 40.9) | 29.4 (20.1, 42.0) | 29.5 (19.6, 40.7) |
Female | 40 (52.0%) | 85 (54.5%) | 38 (50.0%) |
Kellgren-Lawrence grade ≥ 2 | 61 (80.3%) | 95 (61.3%) | 56 (73.7%) |
Baseline BML volume (cm3) | 0.55 (0.16, 10.98) | 0.10 (0.01, 2.94) | 0.15 (0.01, 3.51) |
Baseline medial tibia paBMD | 1.129 (0.681, 1.890) | 1.145 (0.761, 1.743) | 1.111 (0.800, 1.664) |
Baseline M:L paBMD ratio | 1.138 (0.799, 1.549) | 1.096 (0.794, 1.779) | 1.155 (0.914, 1.385) |
Number of knees with baseline BML volume ≥0.50 cm3 | 43 (56%) | 7 (4%) | 21 (27%) |