|
Cohort, n (%)
| | |
|
NHS
|
136 (70.8)
|
405 (71.4)
|
|
NHSII
|
56 (29.2)
|
162 (28.6)
|
|
Caucasian, n (%)
|
190 (99.0)
|
556 (98.1)
|
|
Mean age at blood collection, years (SD)
|
52.3 (8.0)
|
52.4 (8.1)
|
|
Never smoker, n (%)
|
83 (43.2)
|
279 (49.2)
|
|
Current smoker, n (%)
|
33 (17.2)
|
82 (14.5)
|
|
Past smoker, n (%)
|
76 (39.6)
|
206 (36.3)
|
|
Mean pack-years of smokingb (SD)
|
23.1 (16.4)
|
20.8 (18.8)
|
|
Mean alcohol intake, g/day (SD)
|
4.2 (5.6)
|
5.7 (8.9)
|
|
Mean BMI, kg/m2 (SD)
|
26.1 (5.0)
|
25.0 (4.4)
|
|
Premenopausal, n (%)
|
65 (33.9)
|
193 (34.0)
|
|
Parous, n (%)
|
175 (91.1)
|
511 (90.1)
|
|
Irregular menses, n (%)
|
32 (16.7)
|
56 (9.9)
|
|
Positive for any ACPA, n (%)
|
48 (25.0)
|
38 (6.7)
|
|
Positive for anti-CCP, n (%)
|
23 (12.0)
|
0 (0)
|
|
Mean age at RA diagnosis, years (SD)
|
59.9 (9.9)
| |
|
Mean time to RA onset, months (SD)
|
91.1 (53.6)
| |
|
Median time to RA onset, months (IQR)
|
87.5 (92.0)
| |
|
Morning stiffness, n (%)
|
143 (74.5)
| |
|
Arthritis three or more joint areas, n (%)
|
176 (91.7)
| |
|
Hand arthritis, n (%)
|
191 (99.5)
| |
|
Symmetric arthritis, n (%)
|
188 (97.9)
| |
|
Nodules, n (%)
|
21 (10.9)
| |
|
Erosions, n (%)
|
43 (22.4)
| |
