Platelet-derived growth factor
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PDGF
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Stimulation of fibroblast production, chemotaxis, transforming growth factor-β1, collagen production; upregulation of proteoglycan synthesis of fibroblasts, smooth muscle cells, chondrocytes, osteoblasts and mesenchymal stem cells
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Insulin-like growth factor-1
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IGF1
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Promotion of cell growth, differentiation, recruitment in bone, blood vessel, skin, other tissues; upregulation of collagen synthesis with PDGF of fibroblasts
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Transforming growth factor-beta 1
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TGF-β1
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Promotion of fibroblast proliferation, extracellular matrix formation, cell viability, production of collagen from fibroblasts; suppressed interleukin 1-mediated effects on proteoglycan synthesis in cartilage
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Vascular endothelial growth factor
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VEGF
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Promotion of cell growth, migration, new blood vessel growth and anti-apoptosis (anti-cell death) of blood vessel cells
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Basic fibroblastic growth factor
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bFGF
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Stimulation of collagen production, angiogenesis and myoblast proliferation
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Epidermal growth factor
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EGF
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Promotion of cell recruitment, proliferation, differentiation, angiogenesis, cytokine secretion by mesenchymal and epithelial cells
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Connective tissue growth factor
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CTGF
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Promotion of angiogenesis, cartilage regeneration, fibrosis, platelet adhesion
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