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Figure 5 | Arthritis Research & Therapy

Figure 5

From: Efficacy and safety of rituximab treatment in early primary Sjögren's syndrome: a prospective, multi-center, follow-up study

Figure 5

Molecular analysis of minor salivary gland biopsies in the rituximab and disease-modifying anti-rheumatic drug treatment groups. Relative mRNA quantification of (A) LTα, (B) LTβ, (C) CXCR4, (D) CXCL12, (E) CXCR5, (F) CXCL13, and (G) B-cell activating factor (BAFF) was assessed by quantitative real-time polymerase chain reaction in salivary glands obtained from 41 pSS patients and five healthy donors (HD). Bars indicate mean ± standard error of the mean. Levels are expressed as the fold increase or decrease in pSS MSGs compared with HD MSGs. ***P <0.001; **P <0.01 and *P <0.05. DMARD, disease-modifying anti-rheumatic drug; LT, lymphotoxin; RTX, rituximab.

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Arthritis Research & Therapy

ISSN: 1478-6362

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