Table 2 Patient-related outcomes of all patients during 1 year of follow-up a
Early remission | Arm 1 | Arm 2 | OP group | ||
|---|---|---|---|---|---|
Patient characteristics at follow-up visits | (N = 387) | (N = 83) | (N = 78) | P | (N = 50) |
4 months | |||||
DAS | 0.97 (0.40) | 2.49 (0.63) | 2.57 (0.68) | 0.47 | 2.31 (0.63) |
HAQ | 0.23 (0.33) | 0.86 (0.57) | 0.88 (0.57) | 0.77 | 0.73 (0.68) |
MACTAR | 58.2 (15.7) | 52.8 (15.1) | 48.9 (18.8) | 0.14 | 51.6 (14.1) |
MCS | 52.4 (8.0) | 48.8 (9.9) | 50.7 (10.8) | 0.26 | 49.8 (10.5) |
PCS | 51.7 (8.1) | 39.4 (9.7) | 38.1 (9.4) | 0.44 | 42.5 (9.4) |
VASgl, mm | 14 (14) | 37 (21) | 39 (21) | 0.61 | 28 (22) |
VASda, mm | 12 (15) | 42 (24) | 43 (24) | 0.74 | 32 (25) |
VASpain, mm | 10 (14) | 39 (24) | 38 (24) | 0.79 | 27 (24) |
VASms, mm | 11 (17) | 40 (27) | 39 (27) | 0.78 | 32 (30) |
8 months | |||||
DAS | 1.29 (0.69) | 1.97 (0.87) | 2.01 (0.91) | 0.77 | 2.02 (0.84) |
HAQ | 0.35 (0.44) | 0.74 (0.61) | 0.81 (0.64) | 0.51 | 0.68 (0.59) |
MACTAR | 56.4 (15.7) | 55.8 (14.7) | 54.5 (16.1) | 0.60 | 48.9 (19.9) |
MCS | 52.9 (8.4) | 46.6 (17.9) | 48.7 (10.3) | 0.85 | 48.5 (13.0) |
PCS | 48.9 (9.1) | 42.8 (10.9) | 42.5 (11.0) | 0.26 | 43.7 (9.5) |
VASgl, mm | 20 (20) | 33 (23) | 34 (21) | 0.75 | 30 (23) |
VASda, mm | 22 (23) | 39 (26) | 33 (24) | 0.20 | 35 (25) |
VASpain, mm | 19 (23) | 35 (26) | 31 (25) | 0.36 | 32 (24) |
VASms, mm | 24 (26) | 34 (29) | 37 (28) | 0.51 | 40 (27) |
1 year | |||||
DAS | 1.31 (0.78) | 2.07 (0.89) | 1.77 (0.90) | 0.04 | 2.20 (0.83) |
HAQ | 0.38 (0.49) | 0.87 (0.66) | 0.81 (0.66) | 0.60 | 0.77 (0.65) |
MACTAR | 63.0 (9.4) | 59.2 (10.3) | 60.4 (11.9) | 0.54 | 59.7 (11.21) |
MCS | 53.1 (8.6) | 50.5 (10.3) | 50.5 (10.1) | 0.97 | 50.4 (11.9) |
PCS | 48.6 (9.8) | 39.9 (10.3) | 43.0 (11.4) | 0.10 | 42.6 (10.9) |
VASgl, mm | 20 (21) | 33 (23) | 27 (20) | 0.10 | 33 (24) |
VASda, mm | 24 (26) | 42 (29) | 31 (26) | 0.02 | 34 (27) |
VASpain, mm | 21 (23) | 38 (28) | 28 (25) | 0.02 | 28 (25) |
VASms, mm | 25 (26) | 41 (31) | 33 (27) | 0.96 | 39 (30) |
Remission (DAS <1.6) | 263 (68) | 21 (25) | 32 (41) | 0.01 | 11 (22) |