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Table 2 Patient-related outcomes of all patients during 1 year of follow-up a

From: Health-related quality of life and functional ability in patients with early arthritis during remission steered treatment: results of the IMPROVED study

  Early remission Arm 1 Arm 2   OP group
Patient characteristics at follow-up visits (N = 387) (N = 83) (N = 78) P (N = 50)
4 months      
DAS 0.97 (0.40) 2.49 (0.63) 2.57 (0.68) 0.47 2.31 (0.63)
HAQ 0.23 (0.33) 0.86 (0.57) 0.88 (0.57) 0.77 0.73 (0.68)
MACTAR 58.2 (15.7) 52.8 (15.1) 48.9 (18.8) 0.14 51.6 (14.1)
MCS 52.4 (8.0) 48.8 (9.9) 50.7 (10.8) 0.26 49.8 (10.5)
PCS 51.7 (8.1) 39.4 (9.7) 38.1 (9.4) 0.44 42.5 (9.4)
VASgl, mm 14 (14) 37 (21) 39 (21) 0.61 28 (22)
VASda, mm 12 (15) 42 (24) 43 (24) 0.74 32 (25)
VASpain, mm 10 (14) 39 (24) 38 (24) 0.79 27 (24)
VASms, mm 11 (17) 40 (27) 39 (27) 0.78 32 (30)
8 months      
DAS 1.29 (0.69) 1.97 (0.87) 2.01 (0.91) 0.77 2.02 (0.84)
HAQ 0.35 (0.44) 0.74 (0.61) 0.81 (0.64) 0.51 0.68 (0.59)
MACTAR 56.4 (15.7) 55.8 (14.7) 54.5 (16.1) 0.60 48.9 (19.9)
MCS 52.9 (8.4) 46.6 (17.9) 48.7 (10.3) 0.85 48.5 (13.0)
PCS 48.9 (9.1) 42.8 (10.9) 42.5 (11.0) 0.26 43.7 (9.5)
VASgl, mm 20 (20) 33 (23) 34 (21) 0.75 30 (23)
VASda, mm 22 (23) 39 (26) 33 (24) 0.20 35 (25)
VASpain, mm 19 (23) 35 (26) 31 (25) 0.36 32 (24)
VASms, mm 24 (26) 34 (29) 37 (28) 0.51 40 (27)
1 year      
DAS 1.31 (0.78) 2.07 (0.89) 1.77 (0.90) 0.04 2.20 (0.83)
HAQ 0.38 (0.49) 0.87 (0.66) 0.81 (0.66) 0.60 0.77 (0.65)
MACTAR 63.0 (9.4) 59.2 (10.3) 60.4 (11.9) 0.54 59.7 (11.21)
MCS 53.1 (8.6) 50.5 (10.3) 50.5 (10.1) 0.97 50.4 (11.9)
PCS 48.6 (9.8) 39.9 (10.3) 43.0 (11.4) 0.10 42.6 (10.9)
VASgl, mm 20 (21) 33 (23) 27 (20) 0.10 33 (24)
VASda, mm 24 (26) 42 (29) 31 (26) 0.02 34 (27)
VASpain, mm 21 (23) 38 (28) 28 (25) 0.02 28 (25)
VASms, mm 25 (26) 41 (31) 33 (27) 0.96 39 (30)
Remission (DAS <1.6) 263 (68) 21 (25) 32 (41) 0.01 11 (22)
  1. aData are means ± SD, medians (IQR) or numbers (%) as appropriate. ACPA: anticitrullinated protein antibody; DAS: Disease Activity Score; HAQ: Health Assessment Questionnaire; MACTAR: McMaster Toronto Arthritis Patient Preference Questionnaire; MCS: Mental Component Score on the 36-Item Short Form Health Survey; PSC: Physical Component Score on the 36-Item Short Form Health Survey; RA2010: rheumatoid arthritis according to the 2010 American College of Rheumatology and European League against Rheumatism classification criteria; VASda: disease activity; VASgl: global health; VASms: morning stiffness; VASpain: pain. P-value represents the difference in mean scores and remission rates between arms 1 and 2.