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Table 1 Cytokine concentrations in synovial fluid from healthy subjects (n = 5, pooled), and patients with early- (n = 5) and late-stage (n = 5) osteoarthritis

From: Proteomic profiling and functional characterization of early and late shoulder osteoarthritis

Pro-inflammatory interleukins Sample (n = 5) Mean (pg/mL) SD
IL-6 Healthya 98.35  
  EOA 717.9 306.50
  LOA 1492.01 877.62
IL-1β Healthya 0  
  EOA 1.45 1.56
  LOA 4.64 3.29
IL-8 Healthya 0  
  EOA 6.58 6.03
  LOA 38.63 10.35
IL-17A Healthya 0  
  EOA 0.02 0.05
  LOA 0 0
TNF-alpha Healthya 0  
  EOA 0.11 0.11
  LOA 0.51 0.63
IL-18 Healthya 0.48  
  EOA 20.38 8.70
  LOA 37.29 15.36
Anti-inflammatory interleukins    
IL-10 Healthya 1.68  
  EOA 6.39 1.95
  LOA 7.97 3.35
  1. The numeric values depicted for EOA and LOA samples are mean ± SD (concentration range). aCytokine concentrations depicted for healthy synovial fluid samples (n = 5) are values obtained from pooled samples. EOA, early osteoarthritis; LOA, late osteoarthritis.