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Table 3 Comparison of patients with SF cytokine analysis

From: Differences in synovial fluid cytokine levels but not in synovial tissue cell infiltrate between anti-citrullinated peptide/protein antibody-positive and –negative rheumatoid arthritis patients

Variables Total number = 51 ACPA positive number = 40 ACPA negative N = 11 P value
Sex (female,%) 64.7 65.0 63.6 0.93
Age at arthroscopy, years (Mean, SD) 56.8 ± 12.1 58.5 ± 12.2 58.3 ± 1mber2.2 0.64
Disease duration to arthroscopy (months), Median (IQR 25–75) 52.0(12.2–134.3) N = 47 39.3 (8.7–134.3) N = 39 87.9(45.7–147.4) N = 8 0.32
Rheumatoid factor (%) 82 90 54 0.006*
Erosive disease (%) 72 72 70 0.87
Extra-articular disease (%) 37 40 25 0.41
DAS28, Median (IQR 25–75) 5.06 (3.9–5.8) N = 47 5.06 (4.0–5.7) N = 37 5.13 (3.8–5.9) N = 10 0.81
ESR mm/hr (before arthroscopy), Median (IQR 25–75) 43 (22–70) N = 47 43 (24–71) N = 37 27 (16–66) N = 10 0.42
CRP mg/dl (before arthroscopy), Median (IQR 25–75) 3.0 (1.2–6.2) N = 47 3.1 (1.1–6.6) N = 37 2.2 (1.1–6.3) N = 10 0.82
DMARDs (Mean, SD) 2.61 ± 1.50 2.43 ± 1.48 3.27 ± 1.60 0.10
Biologic treatment (%) ever 49 40 82 0.014*
  1. Data are expressed as median (IQR) or as percentage. CRP, C-reactive protein; DMARDs, disease modifying anti-rheumatic drugs; ESR, erythrocyte sedimentation rate; mHAQ, Modified Health Assessment Questionnaire; IQR, interquartile range; SF, synovial fluid; SJC, swelling joint count; TJC, tender joint count. * p value is significant if < 0.05.