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Table 1 Clinical characteristics of the twenty-three patients with Lyme arthritis and of four healthy control subjects*

From: Natural killer cells and natural killer T cells in Lyme arthritis

 

Responsive

Refractory

P value

 

N = 8**

N = 15**

 

Age, years

44 (17-53)

29 (12-78)

0.2

No. male/female

5/3

8/7

0.6

Duration of arthritis (months)

   

 Before treatment

0.1 (0.1-1)

1 (0.1-6)

0.06

 From start of antibiotics to sample date

0 (0-3)

4 (0-18)

0.001

 From start of antibiotics to resolution of arthritis

3 (1.5-3)

10 (4-20)

0.0001

Serum findings on the sample date

   

 Positive serologic result for B. burgdorferi

 antibodies by ELISA and Western blotting

8

15

1.0

Joint fluid findings on the sample date

   

 Total white cell count/mm3

25,750

12,150

0.01

(13,833-60,000)

(5,694-46,250)

 % polymorphonuclear leukocytes

79 (28-91)

88 (16-98)

0.35

 Total mononuclear cells/mm3

1,600

1,500

0.69

(400-6,500)

(320-6,300)

 

 No. PCR+/PCR- for B. burgdorferi DNA

8/0

5/10

0.002

  1. *The four healthy control subjects had a median age of 36 (range, 28 to 42; three were women and one was a man. None had a positive serologic test result for B. burgdorferi antibodies.
  2. **All values are given as median (range) unless otherwise noted. ELISA, enzyme-linked immunosorbent assay.