From: Natural killer cells and natural killer T cells in Lyme arthritis
 | Responsive | Refractory | P value |
---|---|---|---|
 | N = 8** | N = 15** |  |
Age, years | 44 (17-53) | 29 (12-78) | 0.2 |
No. male/female | 5/3 | 8/7 | 0.6 |
Duration of arthritis (months) | Â | Â | Â |
 Before treatment | 0.1 (0.1-1) | 1 (0.1-6) | 0.06 |
 From start of antibiotics to sample date | 0 (0-3) | 4 (0-18) | 0.001 |
 From start of antibiotics to resolution of arthritis | 3 (1.5-3) | 10 (4-20) | 0.0001 |
Serum findings on the sample date | Â | Â | Â |
 Positive serologic result for B. burgdorferi | |||
 antibodies by ELISA and Western blotting | 8 | 15 | 1.0 |
Joint fluid findings on the sample date | Â | Â | Â |
 Total white cell count/mm3 | 25,750 | 12,150 | 0.01 |
(13,833-60,000) | (5,694-46,250) | ||
 % polymorphonuclear leukocytes | 79 (28-91) | 88 (16-98) | 0.35 |
 Total mononuclear cells/mm3 | 1,600 | 1,500 | 0.69 |
(400-6,500) | (320-6,300) | Â | |
 No. PCR+/PCR- for B. burgdorferi DNA | 8/0 | 5/10 | 0.002 |