TY - JOUR AU - Marchesan, Julie Teresa AU - Gerow, Elizabeth Ann AU - Schaff, Riley AU - Taut, Andrei Dan AU - Shin, Seung-Yun AU - Sugai, James AU - Brand, David AU - Burberry, Aaron AU - Jorns, Julie AU - Lundy, Steven Karl AU - Nuñez, Gabriel AU - Fox, David A. AU - Giannobile, William V. PY - 2013 DA - 2013/11/12 TI - Porphyromonas gingivalis oral infection exacerbates the development and severity of collagen-induced arthritis JO - Arthritis Research & Therapy SP - R186 VL - 15 IS - 6 AB - Clinical studies suggest a direct influence of periodontal disease (PD) on serum inflammatory markers and disease assessment of patients with established rheumatoid arthritis (RA). However, the influence of PD on arthritis development remains unclear. This investigation was undertaken to determine the contribution of chronic PD to immune activation and development of joint inflammation using the collagen-induced arthritis (CIA) model. SN - 1478-6354 UR - https://doi.org/10.1186/ar4376 DO - 10.1186/ar4376 ID - Marchesan2013 ER -