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Table 1 Porphyromonas gingivalis oral colonization during periodontitis and arthritis development

From: Porphyromonas gingivalis oral infection exacerbates the development and severity of collagen-induced arthritis

Group Day 0 Day 16 Day 23 Day 30 Day 37 Day 44 Day 51 Day 58 Day 65 Day 73
Baseline 0/8          
D30 Vehicle 0/8    0/8       
D30 Pg 0/8 6/8 6/8 4/8       
D44 Vehicle 0/8    0/8       
D44 Pg 0/8 8/8 8/8 8/8 8/8 8/8     
D44 CFA 0/8      0/8     
D44 Pg-CFA 0/8 8/8 8/8 8/8 8/8 8/8     
D44 IFA 0/8      0/8     
D44 Pg-IFA 0/8 8/8 8/8 8/8 8/8 8/8     
D73 Vehicle 0/8          0/8
D73 Pg 0/8 8/8 8/8 8/8 7/8 8/8 8/8 8/8 6/8 8/8
D73 CFA 0/8          0/8
D73 Pg-CFA 0/8 6/8 7/8 8/8 8/8 8/8 6/8 8/8 8/8 0/8
D73 IFA 0/8          0/8
D73 Pg-IFA 0/8 4/8 8/8 8/8 5/8 8/8 7/8 2/8 6/8 0/8
  1. Murine oral microflora collected at timeline days D0, D16, D23, D30, D37, D44, D51, D58, D65, and D73 were evaluated by polymerase chain reaction of arginine–gingipain (201 base pairs). Values represent the number of infected mice/number of total mice in each group (n = 8). Mice that were not infected with P. gingivalis were not evaluated weekly, but only at baseline and sacrifice. CFA, complete Freund’s adjuvant; IFA, incomplete Freund’s adjuvant; Pg, P. gingivalis.