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Table 1 Clinical data of 17 patients with PTU-induced AAV and 64 patients with primary AAV

From: Epitope analysis of anti-myeloperoxidase antibodies in propylthiouracil-induced antineutrophil cytoplasmic antibody-associated vasculitis

 

PTU-induced AAV

Primary AAV

(n = 17)

(n = 64)

Male/female

2/15

32/32

Age (years)

30.8 ± 15.2

60.48 ± 15.14

Scr (μM)

  

Mean ± SD

75.62 ± 40.64

339.11 ± 237.71

Range

38-176.9

70-1007

Renal insufficiency at diagnosis

13 (76.4%)

48 (75%)

ESR (mm/1 hour)

46.92 ± 38.86

70.05 ± 40.14

Skin rash

5(29.4%)

7 (10.9%)

Arthralgia

9(52.9%)

15(23.4%)

Muscle pain

6 (35.3%)

10 (15.6%)

Lung

6 (35.3%)

43 (67.2%)

ENT

6 (35.2%)

27(42.2%)

Ophthalmic

2 (11.8%)

14(21.9%)

Gastrointestinal

3(17.6%)

11(17.2%)

Nervous system

1 (5.9%)

10(15.6%)

BVAS

  

Mean ± SD

17.1 ± 5.5

20.27 ± 5.18

Range

7-31

13-36

  1. AAV ANCA-associated vasculitis, BVAS Birmingham Vasculitis Activity Scores, ENT ear, nose, and throat, SD standard deviation.