Cohorts | IBS (N = 125) | IBS/FMS (N = 104) | P value |
---|---|---|---|
Gastroduodenal biopsy | |||
 IEL count per 100 epithelial cells | 15 (10) | 27 (26) | <0.001 |
 Marsh stage 0 | 105 (84) | 39 (37) | <0.001 |
 Marsh stage 1 | 20 (16) | 58 (56) | <0.001 |
 Marsh stage 3 | 2 (2) | 7 (7) | <0.001 |
 Helicobacter pylori (+) | 58 (46) | 44 (42) | 0.080 |
CD laboratory biomarkers | |||
 HLA-DQ2 A1/B1 (+) | 30 (24) | 52 (50) | <0.001 |
 IgA anti-tTG-2 serum levels, U/ml | 0.4 (0.1) | 4.7 (20) | <0.001 |