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Table 3 Laboratory results in inflammatory bowel syndrome and fibromyalgia syndrome subgroups a

From: Remarkable prevalence of coeliac disease in patients with irritable bowel syndrome plus fibromyalgia in comparison with those with isolated irritable bowel syndrome: a case-finding study

Laboratory test IBS IBS/FMS cases classified by Marsh stage P value
(N = 125) (N = 104) (Marsh stages 1 and 3 vs. Marsh stage 0)
  Normal mucosa Lymphocytic enteritis Villous atrophy
Marsh stage 0 (n = 39) Marsh stage 1 (n = 58) Marsh stage 3 (n = 7)
IEL count per 100 epithelial cells 15 (10) 14 (2) 35 (5) 37 (5) <0.001
Helicobacter pylori (+) 58 (46) 17 (43) 24 (41) 3 (43) 0.159
HLA-DQ2 A1/B1 (+) 30 (24) 15 (38) 31 (53) 6 (86) 0.052
IgA anti tTG-2, U/ml 0.4 (0.1) 0.5 (0.1) 0.9 (0.7) 60.4 (52) 0.001
  1. aHLA, major histocompatibility complex class II human leucocyte antigen; IBS, irritable bowel syndrome; IBS/FMS, irritable bowel syndrome plus fibromyalgia syndrome; IEL, intraepithelial lymphocyte count per 100 epithelial cells in duodenal biopsy sample; IgA, immunoglobulin A; tTG, tissue transglutaminase. Data are expressed as mean and standard deviation or total and percentage of the total value.