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Table 2 Symptom assessment in the clinical setting

From: Beyond pain in fibromyalgia: insights into the symptom of fatigue

Symptom Sample assessment tools Conditions to consider Objective tests
Activity intolerance BPI pain interference [53] Deconditioning 6 minute walk test
MFI reduced activity [54] Obesity Cardiopulmonary exercise test
30-second chair-stand test
SF-36 role emotional, role physical [55, 56] Neuromuscular disorder Body mass index
Affective GAD-7 [57] Anxiety disorder  
PHQ-9 [58] Generalized anxiety disorder
HADS [59] Depression
CES-D [60] Dysthymia
Somatoform disorder
Autonomic ASP-31 [61] Orthostatic intolerance Thermoregulatory sweat test
Autonomic neuropathies Autonomic reflex screen
Postural orthostatic tachycardia syndrome
Pain BPI [53] Regional pain syndromes Imaging
Pain VAS Neuropathy Electromyography
Inflammatory arthritis Laboratory testing for inflammation
Degenerative arthritis Muscle biopsy
Headaches Quantitative sensory testing
Unrefreshing sleep MOS-Sleep [62] Insomnia Overnight oximetry
Berlin Sleep Questionnaire Obstructive sleep apnea Polysomnography
Restless legs screen Restless legs syndrome Actigraphy
Periodic limb movement disorder
  Sleep phase disorder  
  1. ASP-31, Autonomic Symptom Profile-31; BPI, Brief Pain Inventory; CES-D, Center for Epidemiologic Studies Depression Scale; GAD-7, Generalized Anxiety Disorder questionnaire; HADS, Hospital Anxiety and Depression Scale; MFI, Multidimensional Fatigue Inventory; MOS-Sleep, Medical Outcomes Study Sleep Scale; PHQ-9, Patient Health Questionnaire; SF-36, Medical Outcomes Study Short Form-36; VAS, Visual Analogue Scale.