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Table 3 Sample list of questionnaires that have been used in the assessment of fatigue in clinical trials

From: Beyond pain in fibromyalgia: insights into the symptom of fatigue

Measure Dimensions of fatigue Scaling and number of items Features
Chalder Fatigue Questionnaire [67, 68] Physical and mental 11 items 2-3 minute administration time
4-point Likert scale Higher = worse
Recall period for the past month
Checklist Individual Strength (CIS) [69] Subjective experience, concentration, motivation, and physical activity 20 items 4-5 minute administration time
7-point Likert scale Higher = worse
Designed for chronic fatigue syndrome, but also used with fibromyalgia and healthy populations
Recall period for past 2 weeks
Fatigue Severity Scale (FSS) [70] Physical, social, and cognitive 9 items 2-3 minute administration time
7-point Likert scale Higher = worse
Recall period for the past week
Medical Outcome Study Short Form-36 (SF-36) Vitality Subscale [55, 56] Energy and vitality 4 items 1-2 minute administration time
6-point (version 1) or 5-point (version 2) Likert scale Higher scores = better
Recall period for the past 4 weeks
Multidimensional Assessment of Fatigue (MAF) [64] Severity, stress, degree of interference with activities of daily living, timing, and global 16 items 5-8 minute administration time
10-point rating scales for 1–14, 15 and 16 have 4 ordinal responses Higher scores = worse
Designed for rheumatoid arthritis, but also used in fibromyalgia
Recall period for the past week
Multidimensional Fatigue Inventory (MFI) [54] Global experience and somatic, cognitive, affective, and behavioral symptoms 20 items 4-5 minute administration time
5-point Likert scale Higher scores = worse
Recall period is stated as 'lately’
Visual Analogue Scale (VAS) Any dimension required, typically severity or intensity 1 item <1 minute administration time
   100 mm horizontal line anchored by two statements Recall period typically 1 week, varies