| |
Univariate model
|
Model 1 “Base”
|
Model 2 “metabolic”
|
Model 3 “metabolic + RA”
|
Model 4 “metabolic + RA + steroid”
|
|---|
|
OR (95% CI)
|
P
|
OR (95% CI)
|
P
|
OR (95% CI)
|
P
|
OR (95% CI)
|
P
|
OR (95% CI)
|
P
|
|---|
|
Adiponectin
|
∆SHS ≥ 5
|
1.47 (0.98-2.20)
|
0.06
|
1.7 (1.11-2.61)
|
0.02
|
1.85 (1.16-2.94)
|
0.01
|
2.0 (1.14-3.52)
|
0.02
|
2.0 (1.14-3.52)
|
0.02
|
|
Leptin
|
∆SHS ≥ 5
|
0.73 (0.54-0.97)
|
0.03
|
0.75 (0.55-1.04)
|
0.09
|
0.98 (0.61-1.56)
|
0.92
|
0.97 (0.55-1.68)
|
0.90
|
0.97 (0.56-1.68)
|
0.90
|
|
Visfatin/NAMPT
|
∆SHS ≥ 5
|
1.14 (0.83 1.56)
|
0.41
|
1.12 (0.82-1.54)
|
0.48
|
1.11 (0.79-1.55)
|
0.56
|
0.96 (0.64-1.44)
|
0.85
|
0.96 (0.64-1.44)
|
0.85
|
- OR, odds ratio; 95% CI, 95% confidence interval.
- Multivariate models:
- Model 1 (“base”): sex + age.
- Model 2 (“metabolic”): model 1 + BMI + HOMA-IR index.
- Model 3 (“metabolic + RA”): model 2 + CRP level + DAS28-ESR value + HAQ score + RF status + anti-CCP antibody status + presence of radiographic changes at inclusion.
- Model 4 (“metabolic + RA + steroid”): model 3 + steroid prescription at inclusion.
- The following variables were log-transformed: CRP level, HAQ score, serum adipokine levels. Bold P values are significant.
