Figure 4From: Progranulin antibodies entertain a proinflammatory environment in a subgroup of patients with psoriatic arthritisTumour necrosis factor α–mediated cytotoxicity dependent on progranulin antibody status. (a) After administration of serum and TNF-α to WEHI-S cells, the adsorption of coloured formazan, which is a marker for cell viability, was detected at OD of 450 nm. (b) After administration of serum and TNF-α to HT-1080 cells, the adsorption of coloured formazan was detected at OD of 450 nm. Ab: antibody; PGRN: progranulin; PsA: psoriatic arthritis; PsC: psoriasis without arthritic manifestations.Back to article page