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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Progranulin antibodies entertain a proinflammatory environment in a subgroup of patients with psoriatic arthritis

Figure 4

Tumour necrosis factor α–mediated cytotoxicity dependent on progranulin antibody status. (a) After administration of serum and TNF-α to WEHI-S cells, the adsorption of coloured formazan, which is a marker for cell viability, was detected at OD of 450 nm. (b) After administration of serum and TNF-α to HT-1080 cells, the adsorption of coloured formazan was detected at OD of 450 nm. Ab: antibody; PGRN: progranulin; PsA: psoriatic arthritis; PsC: psoriasis without arthritic manifestations.

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