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Table 5 Genetic risk score analysis

From: Association analysis of the SLC22A11 (organic anion transporter 4) and SLC22A12 (urate transporter 1) urate transporter locus with gout in New Zealand case-control sample sets reveals multiple ancestral-specific effects

  Mean ± standard deviation ū12a t a P a ORb P b Variance explained (%)c
Case Control (95% CI)a (95% CI)
East Polynesian (H) 10.93 ± 1.56 10.45 ± 1.91 0.48 2.71 0.007 1.22 0.002 1.38
(0.13, 0.83) (1.07-1.39)
East Polynesian (L) 4.81 ± 1.70 4.68 ± 1.96 0.13 0.47 0.64 1.03 0.77 0.09
(-0.44, 0.71) (0.84-1.26)
West Polynesian 17.24 ± 1.21 16.57 ± 2.95 0.67 2.43 0.016 1.14 0.041 1.89
(0.13, 1.22) (1.01-1.30)
Polynesian 11.16 ± 1.54 10.23 ± 2.04 0.93 1.54 0.14 1.32 0.21 5.11
(-0.31, 2.18) (0.85-2.05)
European Caucasian 3.02 ± 1.60 2.94 ± 1.52 0.08 0.75 0.45 1.01 0.80 0.04
(-0.13, 0.28) (0.93-1.11)
  1. aū12, difference in means (case (ū1) minus control (ū2)); t, t-value, P, two-tailed t-test P-value. bOR, odds ratio (adjusted by sex); P, logistic regression P-value. cBased on pseudo-R2 calculated during logistic regression.