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Table 1 American College of Rheumatology disease activity measures for rheumatoid arthritis clinical trials: Core Set

From: The ACR20 and defining a threshold for response in rheumatic diseases: too much of a good thing

Disease activity measure
  1 Tender joint count
  2 Swollen joint count
  3 Patient’s assessment of pain
  4 Patient’s global assessment of disease activity
  5 Physician’s assessment of physical function
  6 Patient’s assessment of physical function
  7 Acute-phase reactant value
For trial duration ≥1 year and agent being tested as a ‘DMARD’, also perform:
  8 Radiography or other imaging technique
  1. DMARD disease-modifying anti-rheumatic drug.