Skip to main content

Table 1 Clinical, demographic and serologic data of 55 patients with and without synovitis

From: Patients with rheumatoid arthritis in clinical remission and ultrasound-defined active synovitis exhibit higher disease activity and increased serum levels of angiogenic biomarkers

 

All (n = 55)

Ultrasound-defined active synovitis

P valuea

Yes (n = 25)

No (n = 30)

Age (years)

52.0 (44.0 to 61.5)

51.0 (44.0 to 59.0)

55.0 (47.0 to 63.3)

0.279

Sex (male)

13 (23.6%)

8 (32.0%)

5 (16.7%)

0.311

Body mass index

25.2 (23.2 to 28.3)

26.0 (24.0 to 29.0)

24.0 (23.1 to 27.4)

0.122

Disease duration (months)

90.0 (57.1 to 148.9)

86.3 (60.3 to 153.8)

93.7 (54.9 to 145.2)

0.659

Remission duration (months)

37 (8 to 58)

29 (7.50 to 50.00)

37 (9.00 to 66.25)

0.537

DAS28-ESR

2.03 (1.67 to 2.44)

2.24 (1.94 to 2.55)

1.92 (1.56 to 2.16)

0.060

DAS28-CRP

1.42 (1.38 to 1.58)

1.54 (1.39 to 1.67)

1.40 (1.23 to 1.48)

0.023

SDAI

4.51 (3.56 to 6.21)

5.03 (4.11 to 7.70)

4.14 (2.69 to 6.02)

0.064

Patient global assessment

30 (10 to 30)

30 (10 to 30)

30 (10 to 30)

0.767

Physician global assessment

10 (10 to 30)

10 (10 to 30)

10 (10 to 30)

0.322

VAS pain

9 (2 to 25)

14 (4 to 23)

5 (2 to 25)

0.251

VAS fatigue

15 (2 to 47)

14 (0 to 43)

16 (3 to 57)

0.529

mHAQ

0.1 (0.0 to 0.3)

0.1 (0.0 to 0.3)

0.0 (0.0 to 0.3)

0.570

ESR (mm/1 hour)

9 (7 to 15)

10 (7 to 20)

9 (6 to 12)

0.498

CRP (mg/dl)

0.10 (0.03 to 0.33)

0.11 (0.03 to 0.49)

0.09 (0.04 to 0.23)

0.728

Rheumatoid factor

39 (71%)

18 (72%)

21 (70%)

0.900

Rheumatoid factor (IU)

103 (22 to 229)

84 (22 to 240)

113 (23 to 215)

0.980

ACPA

47 (86%)

23 (92%)

24 (80%)

0.383

ACPA titers (IU/ml)

254 (109 to 1575)

270 (121 to 1352)

226 (83 to 1600)

0.645

Prednisone

15 (27%)

3 (12%)

12 (40%)

0.044

DMARDs

45 (82%)

22 (88%)

23 (77%)

0.463

Biological therapy

23 (42%)

9 (36%)

14 (47%')

0.600

SH (grade ≥2)

31 (56%)

25 (100%)

6 (20%)

<0.001

PDUS

35 (64%)

25 (100%)

10 (33%)

<0.001

  1. Data expressed as median (interquartile range) or as number (percentage). ACPA, anti-cyclic citrullinated peptide/protein antibody; CRP, C-reactive protein; DAS28, 28-joint Disease Activity Score; DMARD, disease-modifying antirheumatic drug; ESR, erythrocyte sedimentation rate; mHAQ. Modified Health Assessment Questionnaire; PDUS, power Doppler ultrasound; SDAI, Simplified Disease Activity Index; SH, synovial hypertrophy; VAS, visual analog scale. aMann–Whitney test.