Chr | Locus | SNP | Minor/major | MAF cases | MAF controls | P MH | OR (CI 95%)a | P BD |
---|---|---|---|---|---|---|---|---|
3 | PPARG | rs310746 | C/T | 0.108 | 0.086 | 1.90E-06 | 1.28 [1.12-1.47] | 0.33 |
4 | CHRNA9 | RHOH | rs6832151 | G/T | 0.315 | 0.281 | 4.30E-06 | 1.17 [1.075-1.27] | 0.05 |
2 | DYSF | rs11692280 | A/G | 0.195 | 0.220 | 2.31E-04 | 0.86 [0.80-0.93] | 0.04 |
4 | PGDS | rs17021463 | T/G | 0.393 | 0.421 | 2.45E-04 | 0.89 [0.83-0.94] | 0.13 |
22 | DGCR6 | rs2543958 | G/T | 0.127 | 0.109 | 4.98E-04 | 1.18 [1.09-1.28] | 0.09 |
17 | ORMDL3/GSDML | rs8079416 | C/T | 0.435 | 0.461 | 1.13E-03 | 0.90 [0.85-0.94] | 0.01 |
1 | - | rs6679637 | A/G | 0.100 | 0.116 | 2.35E-03 | 0.85 [0.77-0.94] | 0.03 |
1 | CSFR3 | rs4653210 | G/T | 0.111 | 0.122 | 3.71E-03 | 0.86 [0.78-0.95] | 0.02 |
3 | PPARG/ TSEN2 | rs9855622 | T/C | 0.124 | 0.110 | 4.75E-03 | 1.14 [1.01-1.30] | 2.94E-03 |
7 | CACNA2D1 | rs1544461 | A/G | 0.429 | 0.409 | 5.14E-03 | 1.09 [1.02-1.16] | 7.81E-04 |
18 | CNDP2 | rs2241508 | G/A | 0.421 | 0.401 | 5.26E-03 | 1.09 [1.03-1.15] | 2.94E-04 |
11 | PHF21A/CREB3L1 | rs7128538 | A/G | 0.491 | 0.470 | 5.51E-03 | 1.09 [1.02-1.16] | 4.62E-03 |
14 | NPAS3 | rs1299512 | G/A | 0.228 | 0.211 | 7.76E-03 | 1.10 [1.00-1.21] | 0.05 |
13 | RFC3 | rs7335534 | G/A | 0.398 | 0.415 | 8.61E-03 | 0.91 [0.84-0.99] | 7.34E-04 |
8 | DDEF1 | rs7817803 | A/C | 0.437 | 0.421 | 0.012 | 1.08 [1.01-1.15] | 2.01E-03 |
8 | DDE/ | rs3057 | C/T | 0.439 | 0.423 | 0.012 | 1.08 [1.01-1.15] | 1.13E-03 |
17 | TMEM132E/CCDC16 | rs887081 | T/G | 0.115 | 0.129 | 0.013 | 0.88 [0.810.95] | 5.33E-03 |
5 | CDH18 | rs1911856 | T/C | 0.059 | 0.048 | 0.013 | 1.18 [1.03-1.35] | 3.24E-03 |
7 | CAV1 | rs2402091 | A/G | 0.110 | 0.122 | 0.014 | 0.88 [0.80-0.97] | 0.02 |
7 | - | rs1228966 | A/G | 0.222 | 0.208 | 0.015 | 1.09 [1.01-1.18] | 2.29E-03 |
7 | SEMA3A | rs1228870 | T/G | 0.222 | 0.208 | 0.017 | 1.09 [1.01-1.18] | 3.15E-03 |
5 | LOC389293 | rs7708428 | G/A | 0.401 | 0.418 | 0.019 | 0.92 [0.87-0.98] | 0.01 |
9 | XPA | rs2808699 | A/C | 0.403 | 0.423 | 0.021 | 0.92 [0.87-0.98] | 2.38E-04 |
8 | DDEF1 | rs7839523 | G/T | 0.440 | 0.425 | 0.021 | 1.07 [1.011-1.14] | 1.10E-03 |
9 | XPA | rs2805790 | A/G | 0.403 | 0.422 | 0.022 | 0.92 [0.87-0.98] | 3.37E-04 |
3 | IRAK2 | rs11706450 | T/C | 0.465 | 0.482 | 0.024 | 0.93 [0.86-1.01] | 9.00E-03 |
9 | XPA | rs2805815 | A/G | 0.403 | 0.422 | 0.024 | 0.93 [0.87-0.99] | 3.02E-04 |
2 | NOL10 | rs4668690 | A/G | 0.067 | 0.059 | 0.026 | 1.15 [1.01-1.30 | 3.10E-03 |
7 | - | rs1029541 | T/C | 0.230 | 0.219 | 0.028 | 1.08 [1.01-1.17] | 8.07E-04 |
9 | XPA | rs2668797 | A/G | 0.071 | 0.112 | 0.029 | 0.933 [0.87-0.99] | 2.48E-04 |
14 | - | rs1036570 | A/G | 0.322 | 0.335 | 0.032 | 0.92 [0.85-1.014] | 2.13E-03 |
3 | - | rs4128236 | T/C | 0.322 | 0.306 | 0.034 | 1.07 [0.98-1.17] | 3.87E-04 |
1 | - | rs10925871 | A/G | 0.193 | 0.181 | 0.038 | 1.08 [1.00-1.17] | 6.22E-03 |
7 | CADPS2 | rs2501439 | G/A | 0.418 | 0.432 | 0.042 | 0.93 [0.87-0.99] | 7.49E-03 |
7 | - | rs757747 | T/C | 0.229 | 0.218 | 0.047 | 1.07 [1.00-1.16] | 1.29E-03 |
7 | WBSCR17 | rs4585627 | T/C | 0.323 | 0.308 | 0.051 | 1.07 [1.00-1.14] | 4.70E-03 |
10 | - | rs1254860 | C/T | 0.110 | 0.100 | 0.064 | 1.09 [0.99-1.21] | 0.03 |
8 | DDEF1 | rs6470805 | G/A | 0.333 | 0.344 | 0.069 | 0.94 [0.88-1.00] | 4.88E-03 |
9 | LCN9 | rs541131 | G/A | 0.400 | 0.385 | 0.071 | 1.06 [0.99-1.12] | 1.78E-03 |
5 | CDH18 | rs2202798 | T/C | 0.080 | 0.069 | 0.078 | 1.11 [0.98-1.24] | 9.17E-04 |
3 | TDGF1 | rs6799581 | G/T | 0.260 | 0.268 | 0.080 | 0.94 [0.86-1.03] | 6.85E-04 |
5 | CDH18 | rs12655266 | A/G | 0.074 | 0.065 | 0.111 | 1.10 [0.98-1.24] | 1.09E-03 |
4 | NPY2R | rs2880417 | G/A | 0.292 | 0.281 | 0.117 | 1.05 [0.99-1.13] | 2.07E-05 |
7 | - | rs10272701 | T/C | 0.192 | 0.183 | 0.130 | 1.06 [0.98-1.15] | 7.73E-03 |
8 | FBX032 | rs3739284 | C/T | 0.219 | 0.224 | 0.148 | 0.94 [0.87-1.01] | 3.71E-03 |
6 | ASCC3 | rs7771570 | C/T | 0.492 | 0.482 | 0.153 | 1.04 [0.98-1.11] | 2.97E-04 |
18 | PHLPP | rs2877745 | T/C | 0.091 | 0.084 | 0.158 | 1.08 [0.98-1.18] | 3.49E-03 |
21 | - | rs2831511 | T/C | 0.393 | 0.403 | 0.175 | 0.95 [0.90-1.01] | 1.54E-04 |
11 | OPCML | rs10894623 | T/G | 0.291 | 0.281 | 0.175 | 1.04 [0.95-1.14] | 8.98E-04 |
6 | ASCC3 | rs6919745 | T/C | 0.476 | 0.467 | 0.190 | 1.042 [0.98-1.11] | 1.88E-04 |
4 | NPY2R | rs13138293 | G/T | 0.308 | 0.299 | 0.195 | 1.05 [0.97-1.11] | 8.20E-05 |
15 | SMAD3 | rs4147358 | A/C | 0.237 | 0.243 | 0.203 | 0.95 [0.86-1.04] | 4.76E-04 |
17 | TMEM132E | rs4795032 | T/C | 0.351 | 0.341 | 0.232 | 1.04 [0.95-1.13] | 6.65E-04 |
9 | - | rs10756265 | A/G | 0.342 | 0.352 | 0.251 | 0.96 [0.90-1.02] | 2.18E-04 |
9 | - | rs443042 | G/A | 0.366 | 0.376 | 0.261 | 0.96 [0.90-1.02] | 2.01E-04 |
9 | SUSD3 | rs9696357 | T/C | 0.154 | 0.160 | 0.268 | 0.95 [0.87-1.03] | 2.11E-03 |
12 | SFRS8 | rs10794423 | C/T | 0.439 | 0.442 | 0.282 | 0.96 [0.89-1.04] | 1.22E-03 |
2 | ATP6V1C2 | rs7422405 | A/G | 0.428 | 0.433 | 0.385 | 0.97 [0.91-1.03] | 1.93E-04 |
3 | RBMS3 | rs35883 | A/G | 0.457 | 0.4564 | 0.556 | 1.019 [0.94-1.10] | 1.04E-04 |
21 | CHODL/ PRSS7 | rs2248200 | C/T | 0.484 | 0.4815 | 0.598 | 1.01 [0.96-1.07] | 1.35E-03 |
21 | CHODL/PRSS7 | rs1688165 | A/G | 0.485 | 0.4820 | 0.628 | 1.01 [0.96-1.07] | 8.62E-04 |
16 | ZNF423 | rs1477020 | T/C | 0.121 | 0.1235 | 0.649 | 0.97 [0.86-1.10] | 8.30E-06 |
1 | C1QB | rs631090 | C/T | 0.073 | 0.0702 | 0.729 | 1.02 [0.90-1.15] | 3.73E-04 |
16 | ZNF423 | rs1990629 | G/A | 0.128 | 0.1308 | 0.736 | 0.98 [0.87-1.10] | 2.13E-05 |
11 | OPCML | rs11223273 | T/C | 0.275 | 0.2721 | 0.759 | 1.01 [0.92-1.10] | 1.40E-04 |
19 | TSPAN16 | rs322151 | T/C | 0.252 | 0.2527 | 0.990 | 0.99 [0.94-1.06] | 3.37E-04 |