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Table 1 Correlation analysis

From: Intra-articular injection of collagenase in the knee of rats as an alternative model to study nociception associated with osteoarthritis

Pearson correlation coefficient
  One week Six weeks
  250 U 500 U 250 U 500 U
vs KB CW KB CW KB CW KB CW
Knee diameter 0.768 −0.137 0.791 0.136 −0.017 0.564 −0.152 0.350
  ** - ** - - - - -
CMLW 0% 0.474 −0.389 0.929 −0.732 0.764 −0.436 0.808 −0.710
  - - *** * * - ** *
CMLW 50% - - 0.506 −0.495 - - 0.569 −0.609
  - - - - - - - -
CMLW 100% - - - - - - 0.456 −0.221
  - - - - - - - -
TCDW 0.674 −0.407 0.801 −0.358 0.871 −0.341 0.853 −0.696
  * - ** - ** - ** *
SCDW 0.260 −0.193 0.414 −0.005 0.516 0.109 0.880 −0.630
  - - - - - - ** -
ZDR Z1 0.433 −0.536 0.331 0.034 0.452 0.068 0.487 −0.526
  - - - - - - - -
ZDR Z2 0.891 −0.311 0.695 −0.328 0.747 −0.099 0.880 −0.662
  *** - * - * - ** -
ZDR Z3 0.8032 0.147 0.598 −0.143 0.693 0.030 0.795 −0.453
  ** - - - * - * -
CDS Z1 0.259 0.010 0.340 0.019 0.604 0.011 0.8182 −0.576
  - - - - - - ** -
CDS Z2 0.425 −0.079 0.543 −0.442 0.704 −0.425 0.863 −0.711
  - - - - * - ** *
CDS Z3 0.434 −0.255 0.551 −0.344 0.565 −0.476 0.659 −0.491
  - - - - - - - -
OS - - - - 0.179 −0.446 0.390 −0.606
  - - - - - - - -
SMIS 0.341 0.004 0.611 −0.153 0.582 −0.204 0.860 −0.433
  - - * - - - ** -
MJCR 0.621 0.114 0.279 0.0609 −0.190 −0.076 0.450 −0.546
  - - - - - - - -
GPT 0.431 −0.106 0.592 −0.124 −0.007 0.142 0.745 −0.354
  - - - - - - * -
  1. *P <0.05, **P <0.01, ***P <0.01.
  2. Pearson’s correlation analysis between Knee-Bend score or %TIPPI and knee diameter or the histopathology score parameters at one and six weeks for 250 U and 500 U collagenase-injected animals. CDS, Cartilage degeneration score; CMLW, Cartilage matrix loss width; GPT, Growth plate thickness; MJCR, Medial joint capsule repair; OS, Osteophytes score; SCDW, Significant cartilage degeneration width; SMIS, Synovial membrane inflammation score; TCDW, Total cartilage degeneration width; ZDR, Zonal depth ratio.