Correlation of IFN score, STAT1, ADAR, CCL2, CXCL10, and miR-146a levels to systemic lupus erythematosus (SLE) disease activity. (A) IFN score, (B) STAT1, (C) ADAR, (D) CCL2, and (E) CXCL10 were significantly elevated in SLE patient visits (active and inactive disease activity are indicated as + and - respectively) compared to healthy donors (HD). No statistical difference was detected between active and inactive SLE for IFN score, ADAR, or CXCL10. (F-H) TNFα, pri-miR-146a, and miR-146a did not show any significant difference among the groups. STAT, signal transducers and activators of transcription; ADAR, adenosine deaminase acting on RNA; CCL2, C-C motif chemokine ligand 2; CXCL10, C-X-C motif chemokine 10.