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Figure 6 | Arthritis Research & Therapy

Figure 6

From: Elevated signal transducers and activators of transcription 1 correlates with increased C-C motif chemokine ligand 2 and C-X-C motif chemokine 10 levels in peripheral blood of patients with systemic lupus erythematosus

Figure 6

High levels of CCL2, CXCL10, and miR-146a compared to low STAT1 in high STAT1 systemic lupus erythematosus (SLE) patients. (A) IFN score, (B) ADAR, (C) CCL2, (D) CXCL10, (E) pri-miR-146a, and (F) miR-146a were compared in SLE patient visits and healthy donors (HD), which were segregated by high and low STAT1 levels demonstrating that patients with high STAT1 SLE expressed higher levels of CCL2, CXCL10, and miR-146a than those with low STAT1. STAT, signal transducers and activators of transcription; ADAR, adenosine deaminase acting on RNA; CCL2, C-C motif chemokine ligand 2; CXCL10, C-X-C motif chemokine 10.

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