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Table 4 Willingness to pay and willingness to trade efficacy for osteoporosis medication attributes a

From: Patients’ preferences for osteoporosis drug treatment: a discrete-choice experiment

Attributes and levels

Willingness to pay

Willingness to trade efficacy

(€ per month)

(% risk reduction)

Efficacy (1% risk reduction)

3.73 (3.01 to 4.44)

Cost (€1)

-2.27 (–1.58 to –2.96)

Drug administration (reference level: weekly oral tablet)

 

 Monthly oral tablet

16.16 (12.85 to 19.47)

-10.16 (–7.88 to –12.50)

 Subcutaneous injection 3-monthly

4.24 (3.72 to 4.76)

-2.93 (–2.57 to –3.30)

 Subcutaneous injection 6-monthly

19.53 (17.15 to 21.92)

-13.52 (–11.82 to –15.22)

 Intravenous injection 3-monthly

-15.28 (–23.23 to –7.34)

8.66 (14.31 to 3.01)

 Intravenous injection yearly

11.75 (5.64 to 17.85)

-5.83 (–1.88 to –9.77)

Side-effects (reference level: gastrointestinal disorders)

 

 Flu-like symptoms

25.21 (13.06 to 20.50)

-16.68 (–14.20 to –19.16)

 Skin reactions

16.78 (13.06 to 20.50)

-9.48 (–7.13 to –11.83)

  1. Data presented as mean (95% confidence interval). A positive willingness to pay means that patients are willing to pay a personal contribution for the attribute/level, while a negative willingness to trade efficacy means that patients are willing to give up treatment efficacy for the attribute/level. aUsing the conditional constrained distribution.