Figure 5

Cellular-expressed and shed CD18 attributed to peripheral blood mononuclear cell (PBMC) source. (A) The cell membrane expression of CD18 on T cells, natural killer (NK) cells, and monocytes using PBMCs from a representative healthy control (HC) with the gating strategy indicated. (B) The cell membrane expression of CD18 on T cells, NK cells, and monocytes using PBMCs from 10 HCs and 2 patients with spondyloarthritis (SpA). Levels of CD18 expression were measured by the median fluorescence intensity (MFI). Bars indicate median and interquartile range. (C) The concentration of sCD18 in supernatants from cultured T cells, NK cells, and monocytes derived from PBMCs from 5 HCs. Bars indicate median and interquartile range. ***P <0.001.