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Table 2 Baseline characteristics of the patients who developed Pneumocystis pneumonia a

From: Prophylaxis for Pneumocystis pneumonia in patients with rheumatoid arthritis treated with biologics, based on risk factors found in a retrospective study

Patient

Biologic

Age (years)

Sex

RA duration (months)b

Treatment duration (months)c

Pulmonary disease

DM

DAS28 score (ESR)

PSL (mg)

KL-6 (U/ml)

1

IFX

71

Female

72

10

(-)

(-)

6.24

2.5

ND

2

IFX

78

Female

79

1

(+)

(-)

6.99

1.0

178

3

IFX

62

Male

21

20

(+)

(-)

7.40

2.0

893

4

IFX

78

Female

40

1

(+)

(-)

8.04

8.0

398

5

IFX

57

Male

5

2

(+)

(-)

3.38

0

304

6

ETN

73

Male

2

3

(+)

(-)

7.20

50

366

7

ETN

59

Female

252

15

(-)

(-)

5.60

1.0

224

8

ETN

75

Male

132

5

(+)

(-)

6.75

5.0

624

9

TCZ

73

Male

84

8

(+)

(-)

7.00

10

445

Mean

 

69.5

 

76.3

7.2

7/9

0/9

6.51

8.83

429

  1. aPCP developed in nine patients who did receive trimethoprim/sulfamethoxazole prophylaxis. Eight of nine patients were given glucocorticoids. -: Without DM; +: With DM; DAS28: Disease Activity Score in 28 joints; DM: Diabetes mellitus; ESR: Erythrocyte sedimentation rate; ETN: Etanercept; IFX: Infliximab; PCP: Pneumocystis pneumonia; PSL: Prednisolone; RA: Rheumatoid arthritis; TCZ: Tocilizumab. bRA duration was measured between the onset of RA and the initiation of biologics. cTreatment duration was measured between the initiation of biologics and PCP development.