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Table 5 Multivariable analysis of factors associated with serum anti-nuc levels in patients with SLE

From: Serum nitrated nucleosome levels in patients with systemic lupus erythematosus: a retrospective longitudinal cohort study

Variable

Category/term

Ratio (95% CI)

P-value

Gender

Female

1

 
 

Male

2.83 (1.72, 4.69)

<0.001

Disease duration

Ratio given per 5-year increase

0.87 (0.78, 0.98)

0.02

Age (at diagnosis)

Ratio given per 10-year increase

0.59 (0.49, 0.72)

<0.001

RNP

No

1

 
 

Yes

0.47 (0.32, 0.70)

<0.001

dsDNA

Ratio given per 10-fold increase (1 unit on log scale)

1.79 (1.40, 2.28)

<0.001

C3

Ratio given per 0.1 g/l increase

0.29 (0.15, 0.56)

<0.001

NN level

Ratio given per 10-fold increase (1 unit on log scale)

0.88 (0.72,1.07)

0.20

  1. Anti-nuc, Anti-nucleosome antibody; dsDNA, double stranded DNA; RNP, ribonucleoprotein; SLE, systemic lupus erythematosus.