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Table 5 Multivariable analysis of factors associated with serum anti-nuc levels in patients with SLE

From: Serum nitrated nucleosome levels in patients with systemic lupus erythematosus: a retrospective longitudinal cohort study

Variable Category/term Ratio (95% CI) P-value
Gender Female 1  
  Male 2.83 (1.72, 4.69) <0.001
Disease duration Ratio given per 5-year increase 0.87 (0.78, 0.98) 0.02
Age (at diagnosis) Ratio given per 10-year increase 0.59 (0.49, 0.72) <0.001
RNP No 1  
  Yes 0.47 (0.32, 0.70) <0.001
dsDNA Ratio given per 10-fold increase (1 unit on log scale) 1.79 (1.40, 2.28) <0.001
C3 Ratio given per 0.1 g/l increase 0.29 (0.15, 0.56) <0.001
NN level Ratio given per 10-fold increase (1 unit on log scale) 0.88 (0.72,1.07) 0.20
  1. Anti-nuc, Anti-nucleosome antibody; dsDNA, double stranded DNA; RNP, ribonucleoprotein; SLE, systemic lupus erythematosus.