Table 4 Correlation of carotid and femoral artery intima-media thickness with traditional and nontraditional risk factors for atherosclerosis a
Variable | SSc (n = 90) | SLE (n = 100) | ||||||
|---|---|---|---|---|---|---|---|---|
Mean CCA IMT | Mean CFA IMT | Mean CCA IMT | Mean CFA IMT | |||||
Correlation | P value | Correlation | P value | Correlation | P value | Correlation | P value | |
Age (years) | r = 0.682 | <0.001 | r = 0.565 | <0.001 | r = 0.726 | <0.001 | r = 0.560 | <0.001 |
Age at diagnosis (years) | r = 0.652 | <0.001 | r = 0.586 | <0.001 | r = 0.670 | <0.001 | r = 0.437 | <0.001 |
Disease duration (months) | r = -0.030 | 0.782 | r = -0.109 | 0.308 | r = 0.094 | 0.357 | r = 0.217 | 0.032 |
Male sex | r φ = 0.261 | 0.013 | r φ =0.341 | 0.001 | r φ = 0.268 | 0.007 | r φ = 0.208 | 0.039 |
Postmenopausal status | r = 0.546 | 0.001 | r = 0.375 | 0.001 | r = 0.400 | <0.001 | r = 0.373 | <0.001 |
Body mass index | r = 0.128 | 0.241 | r = 0.197 | 0.070 | r = 0.258 | 0.012 | r = 0.294 | 0.004 |
Systolic blood pressure (mmHg) | r = 0.303 | 0.007 | r = 0.332 | 0.003 | r = 0.346 | 0.001 | r = 0.171 | 0.124 |
Glomerular filtration rate | r = -0.316 | 0.003 | r = -0.489 | <0.001 | r = -0.296 | 0.003 | r = -0.277 | 0.006 |
Nicotine pack-years | r = 0.022 | 0.839 | r = 0.320 | 0.002 | r = 0.082 | 0.424 | r = -0.058 | 0.570 |
Coronary heart disease | r φ = 0.160 | 0.133 | r φ = 0.379 | <0.001 | r φ = 0.265 | 0.008 | r φ = 0.160 | 0.115 |
mRSS | r = 0.225 | 0.036 | r = -0.021 | 0.843 | – | – | – | – |
SCL70 antibody | r φ = -0.117 | 0.270 | r φ = -0.209 | 0.048 | – | – | – | – |
Centromere antibody | r φ = 0.165 | 0.119 | r φ = 0.255 | 0.015 | – | – | – | – |
SLEDAI | – | – | – | – | r = -0.166 | 0.115 | r = -0.057 | 0.591 |
SLICC | – | – | – | – | r = 0.208 | 0.049 | r = 0.117 | 0.271 |
dsDNA antibody | – | – | – | – | r φ = -0.188 | 0.063 | r φ = -0.197 | 0.051 |
Nucleosomes antibody | – | – | – | – | r φ = -0.231 | 0.021 | r φ = -0.123 | 0.224 |