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Table 5 Linear regression analysis of factors associated with carotid and femoral artery intima-media thickness in systemic sclerosis and systemic lupus erythematosus patients

From: Atherosclerotic plaques occur in absence of intima-media thickening in both systemic sclerosis and systemic lupus erythematosus: a duplexsonography study of carotid and femoral arteries and follow-up for cardiovascular events

Variable Mean CCA IMT Mean CFA IMT
Standardized beta coefficient Regression coefficient (95% CI) P value Standardized beta coefficient Regression coefficient (95% CI) P value
Systemic sclerosis a (Constant 0.349; R2 = 50.5%) (Constant 0.762; R2 = 49.9%)
Age (per year) 0.664 0.007 (0.005 to 0.008) <0.001 0.336 0.004 (0.002 to 0.007) 0.003
Male sex 0.202 0.088 (0.022 to 0.153) 0.012 0.245 0.138 (0.025 to 0.251) 0.018
Glomerular filtration rate (per unit) -0.302 -0.003 (0.000 to 0.004) 0.005
Nicotine use (per pack-year) 0.198 0.002 (0.000 to 0.004) 0.046
Systemic lupus erythematosus b (Constant 0.392; R2 = 52.7%) (Constant 0.452; R2 = 31.3%)
Age (per year) 0.726 0.006 (0.005 to 0.008) <0.001 0.560 0.005 (0.004 to 0.007) <0.001
  1. CCA, common carotid artery; CFA, common femoral artery; CI, confidence interval; IMT, intima-media thickness.
  2. aMultivariate linear regression model for mean CCA IMT and CFA IMT of systemic sclerosis patients. bSimple linear regression model, other additional variables in multivariate analysis did not significantly improve the model for both mean CCA IMT and CFA IMT of systemic lupus erythematosus patients.
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