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Figure 2 | Arthritis Research & Therapy

Figure 2

From: Angiotensin receptor type 1 and endothelin receptor type A on immune cells mediate migration and the expression of IL-8 and CCL18 when stimulated by autoantibodies from systemic sclerosis patients

Figure 2

Angiotensin II receptor type 1 protein expression in monocytes of systemic sclerosis patients correlates negatively with disease duration. Frequency of angiotensin II receptor type 1 (AT1R)-positive CD14+ monocytes shows a significant negative correlation with (A) the time since onset of Raynaud’s phenomenon (patients with reported onset of Raynaud’s phenomenon; n = 16) and (B) the time since onset of the first non-Raynaud’s symptom presenting the onset of the disease (patients with reported onset of the first non-Raynaud’s symptom; n = 16). Statistical analysis was done by Spearman’s correlation. *P < 0.05.

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