Figure 5

Confocal laser scanning microscopy images showing cellular differences between wild-type and dedicator of cytokinesis 2 ( Dock2 ) gene mutant mice. (A,B) The morphology of healthy chondrocytes in the superficial zone of articular cartilage from wild-type mice. (C,D) The loss of chondrocytes in the superficial zone of the articular cartilage from Dock2 gene mutant mice. X and Y coordinates indicate images that were parallel to the cartilage surface and taken from a transverse view.