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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Promising potential of new generation translocator protein tracers providing enhanced contrast of arthritis imaging by positron emission tomography in a rat model of arthritis

Figure 4

Tissue distribution of [11C]DPA-713 and [18F]DPA-714 with and without blocking of TSPO binding with unlabelled PK11195. Tissue distribution of (A) [11C]DPA-713 and (B) [18F]DPA-714 in arthritic rats with (grey bars) and without (black bars) blocking of TSPO binding with 5 mg/kg unlabelled PK11195. Results are presented as mean ± SD of seven arthritic rats for [11C]DPA-713, six arthritic rats for [18F]DPA-714 and two arthritic rats per tracer for blocking experiments. SD, standard deviation; TSPO, translocator protein.

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