Figure 1

Cerebrospinal fluid (CSF) antibodies to the N-methyl-D-aspartate (NMDA) receptor subunit NR2 (anti-NR2) in neuropsychiatric systemic lupus erythematosus (NPSLE). (A) Comparison between NPSLE and non-SLE controls, (B) comparison among various subtypes of NPSLE. ACS, acute confusional state; Non-ACS, diffuse NPSLE other than ACS, including anxiety disorder, cognitive dysfunction, mood disorder and psychosis; Focal, focal NPSLE. Statistical analysis was performed by the Mann-Whitney U-test (A) and the Kruskal-Wallis test with the Dunn multiple comparison test (B).