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Table 2 Correlation coefficients (rho) between the bone traits in the JIA cohort and controls

From: Bone mass and quality in patients with juvenile idiopathic arthritis: longitudinal evaluation of bone-mass determinants by using dual-energy x-ray absorptiometry, peripheral quantitative computed tomography, and quantitative ultrasonography

pQCT phenotypes DXA Phenotypes QUS phenotypes
  TrbBMD CrtBMD Total density CBA Bone area Muscle CSA Fat CSA SSIp BMAD BMD QUS z-score AD-SoS BTT
TrbBMD   0.13 0.60*** 0.10 0.14 0.26* 0.16 0.05 0.12 0.12 - 0.05 0.01 0.07
0.19 0.59^^^ 0.23^ 0.19 0.31^^ 0.29^ 0.28^ 0.35^^ 0.15 0.09 0.14 0.18
0.25° 0.78°°° 0.32°° 0.24° 0.35°° −0.10 −0.26° 0.39°° 0.44°° 0.17 0.12 0.31°
CrtBMD    0.34** 0.23* 0.14 0.42*** 0.09 0.36** 0.49** 0.69*** 0.21* 0.60*** 0.64***
0.50^^^ 0.52^^^ 0.28^ 0.39^^ 0.16 0.41^^ 0.46^^ 0.72^^^ 0.22^ 0.70^^^ 0.66^^^
0.39°° 0.83°°° 0.49°° 0.70°°° - 0.27° 0.39°° 0.63°°° 0.80°°° 0.61°°° 0.72°°° 0.82°°°
Tot density     0.11 0.19 0.41** 0.23 0.22* 0.12 0.46** 0.27* 0.43*** 0.40***
0.39^^ 0.15 0.38^^ −0.20 0.23^ 0.36^^ 0.48^^ 0.24^ 0.50^^ 0.42^^
0.61°°° 0.29° 0.59°°° 0.10 0.32°° 0.24° 0.56°°° 0.18 0.35°° 0.43°°
CBA      0.11 0.22* - 0.26* 0.25* - 0.09 0.28** 0.12 0.24* 0.25*
0.49^^ 0.81^^^ −0.16 0.83^^^ 0.25^ 0.71^^^ 0.31^^ 0.48^^ 0.72^^^
0.82°°° 0.92°°° 0.14 0.42°°° 0.34°° 0.89°°° 0.57°°° 0.26° 0.85°°°
Bone area       0.49** 0.05 0.55** 0.20 0.18 0.05 0.18 0.30**
0.49^^ 0.11 0.66^^ 0.31^^ 0.40^^ 0.09 0.19 0.37^^
0.78°°° 0.37°° 0.72°°° 0.22° 0.75°°° 0.27° 0.47°° 0.71°°°
MuscleCSA        - 0.27* 0.47*** 0.53*** 0.66*** 0.15 0.48** 0.76***
−0.37^^ 0.63^^^ 0.42^^ 0.61^^^ 0.13 0.70^^^ 0.80^^^
0.02 0.38°° 0.34°° 0.86°°° 0.19 0.67°°° 0.85°°°
FatCSA         −040** 0.11 0.13 - 0.19* - 0.11 - 0.14
−0.48^^ −0.14 0.38^^ −0.05 −0.18 −0.16
0.19 0.37°° 0.39°° −0.22°° −0.43°° −0.31°°
SSIp          0.25* 0.52*** 0.02 0.35** 0.56***
0.21^ 0.53^^^ 0.11 0.31^^ 0.51^^^
0.24° 0.69°°° 0.16 0.53°°° 0.67°°°
BMAD           0.38*** - 0.01 0.16 0.02
0.40^^ 0.21^ 0.28^ 0.19
0.29° 0.39°° 0.57°°° 0.68°°°
BMD            0.31** 0.78*** 0.87***
0.28^ 0.76^^^ 0.72^^^
0.71°° 0.67°°° 0.86°°°
QUS z-score             0.56*** 0.68***
0.51^^^ 0.59^^^
0.54°°° 0.65°°°
AD-SoS              0.73***
0.68^^^
0.86°°°
  1. The first line of each cell describes the correlation between bone parameters during transversal study of JIA patients; the second line of each cell describes the correlation between bone parameters during longitudinal study of JIA patients; the third line of each cell describes the correlation between bone parameters during transversal study of controls.
  2. *JIA transversal study: *P < 0.05; **P < 0.005; ***P < 0.0005; JIA longitudinal study: ^P < 0.05; ^^P < 0.005; ^^^P < 0.0005; °Controls transversal study: °P < 0.05; °°P < 0.005; °°°P < 0.0005. AD-SoS, amplitude-dependent speed of sound; BTT, bone transmission time. CBA, cortical bone area; CrtBMD, cortical bone mineral density; FatCSA, fat cross-sectional area; JIA, juvenile idiopathic arthritis; a; MuscleCSA, muscle cross-sectional area; SSIp, density-weighted polar section modulus; QUS, quantitative ultrasonography; Tot density, total density. TrbBMD, trabecular bone mineral density.