Bosentan reverses the pro-fibrotic phenotype of systemic sclerosis dermal fibroblasts via increasing DNA binding ability of transcription factor Fli1

Table 1 Viability of systemic sclerosis dermal fibroblasts in the presence or absence of bosentan, which was evaluated by trypan blue exclusion test

The impact of bosentan on cell viability was evaluated by trypan blue exclusion test. The percentage of cell viability was calculated according to the following formula: % cell viability = (viable cell count/total cell count) × 100. Data are expressed as the mean ± SD of results in three independent experiments.

ISSN: 1478-6362