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Table 5 Genetic analysis results

From: Genetic, clinical and radiographic signs in knee osteoarthritis susceptibility

Polymorphism Genotype Group A (n = 20) % HWe P value Group B (n = 21) % HWe P value Group C (n = 21) % HWe P value
FRZB (rs288326; OS1A)           
 CC WT 17 85 0.05 14 66.7 0.36 15 75 0.33
 CT H 2 10 7 33.3 4 20
 TT MUT 1 5   0 0   1 5  
FRZB (rs7775; OS1B)           
 CC WT 18 90 0.03 16 76.2 0.54 13 65 0.34
 CG H 2 10 5 23.8 7 35
 GG MUT 0 0 0 0 0 0
MATN3 (rs77245812; OS2)           
 CC WT 19 95 0.91 20 95.2 0.91 18 90 0.81
 CT H 1 5 1 4.8 2 10
 TT MUT 0 0 0 0 0 0
ASPN (D14; OS3)           
 D13 WT 5 25 0.65 3 14.3 0.12 4 20 0.65
 D13/D14 H 11 55 14 66.7 11 55
 D14 MUT 4 20 4 19 5 25
PTH2R (rs144641723; OS4)           
 GG WT 19 95 0.91 21 100 NA 20 100 NA
 GT H 1 5 0 0 0 0
 TT MUT 0 0 0 0 0 0
GDF5 (rs143383; OS5)           
 TT WT 3 15 0.18 12 57.1 0.04 7 35 0.44
 TC H 13 65 5 23.8 11 55
 CC MUT 4 20 4 19 2 10
DVWA (rs11718863; OS6)           
 TT WT 15 75 0.33 17 81 0.63 9 45 0.39
 TA H 4 20 4 19 10 50
 AA MUT 1 5 0 0 1 5
  1. D, aspartic acid repeat; FRZB, frizzled-related protein; GDF5, growth and differentiation factor 5; H, heterozygote; HWe, Hardy–Weinberg equilibrium; MUT, homozygote; NA, not available; OS, osteoarthritis susceptibility; PTHR2, parathyroid hormone 2; WT, wild type.