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Table 5 Age in relation to radiological progression a

From: Age at onset determines severity and choice of treatment in early rheumatoid arthritis: a prospective study

Covariates OR 95% CI P-value
Age at disease onsetb 1.842 1.014 to 3.348 <0.05
Female sex 0.361 0.189 to 0.692 <0.01
ACPA-positive 2.473 1.282 to 4.769 <0.01
ESR (T0), mm/h 1.010 0.997 to 1.024 0.136
CVD-related comorbidityc 0.889 0.460 to 1.718 0.727
Corticosteroids (ever) ≤T5, yes 0.892 0.488 to 1.631 0.711
  1. aACPA, Anticyclic citrullinated peptide/protein; CI: Confidence interval; CVD, Cardiovascular disease; DMARD, Disease-modifying antirheumatic drug; ESR, Erythrocyte sedimentation rate; OR: Odds ratio. bAge at disease onset stratified as young-onset rheumatoid arthritis <58 years old and late-onset rheumatoid arthritis ≥58 years old. bCVD-related comorbidity at time of inclusion (T0): CVD, hypertension or diabetes mellitus present before T0. cRadiological progression is defined as the difference between Larsen score at 24 months and Larsen score at baseline (Δ Larsen score) ≥3. Data are derived from multiple logistic regression (n = 236).